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Brain aging mechanisms with mechanical manifestations
Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …
Brain age and other bodily 'ages': implications for neuropsychiatry
As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …
Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy
Some humans age faster than others. Variation in biological aging can be measured in
midlife, but the implications of this variation are poorly understood. We tested associations …
midlife, but the implications of this variation are poorly understood. We tested associations …
Brain structure and cognitive ability in healthy aging: a review on longitudinal correlated change
Little is still known about the neuroanatomical substrates related to changes in specific
cognitive abilities in the course of healthy aging, and the existing evidence is predominantly …
cognitive abilities in the course of healthy aging, and the existing evidence is predominantly …
Brain-age in midlife is associated with accelerated biological aging and cognitive decline in a longitudinal birth cohort
An individual's brainAGE is the difference between chronological age and age predicted
from machine-learning models of brain-imaging data. BrainAGE has been proposed as a …
from machine-learning models of brain-imaging data. BrainAGE has been proposed as a …
What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus
What can be expected in normal aging, and where does normal aging stop and pathological
neurodegeneration begin? With the slow progression of age-related dementias such as …
neurodegeneration begin? With the slow progression of age-related dementias such as …
Entorhinal tau pathology, episodic memory decline, and neurodegeneration in aging
The medial temporal lobe (MTL) is an early site of tau accumulation and MTL dysfunction
may underlie episodic-memory decline in aging and dementia. Postmortem data indicate …
may underlie episodic-memory decline in aging and dementia. Postmortem data indicate …
Differential longitudinal changes in cortical thickness, surface area and volume across the adult life span: regions of accelerating and decelerating change
Human cortical thickness and surface area are genetically independent, emerge through
different neurobiological events during development, and are sensitive to different clinical …
different neurobiological events during development, and are sensitive to different clinical …
The ageing brain: age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia
Background Anaesthetic drugs act at sites within the brain that undergo profound changes
during typical ageing. We postulated that anaesthesia-induced brain dynamics observed in …
during typical ageing. We postulated that anaesthesia-induced brain dynamics observed in …
Structural imaging of hippocampal subfields in healthy aging and Alzheimer's disease
Hippocampal atrophy, as evidenced using magnetic resonance imaging (MRI), is one of the
most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD) …
most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD) …