Mitochondria are cellular organelles responsible for generation of chemical energy in the
process called oxidative phosphorylation. They originate from a bacterial ancestor and …

Mitochondria are one of the most important organelles in cells. Mitochondria are semi-
autonomous organelles with their own genetic system, and can independently replicate …

Cryo-electron microscopy (cryo-EM) has become a leading technology for determining
protein structures. Recent advances in this field have allowed for atomic resolution …

The mitochondrial translation system originates from a bacterial ancestor but has
substantially diverged in the course of evolution. Here, we use single-particle cryo-electron …

Mitochondria control life and death in eukaryotic cells. Harboring a unique circular genome,
a by‐product of an ancient endosymbiotic event, mitochondria maintains a specialized and …

Assembly of the mitoribosome is largely enigmatic and involves numerous assembly factors.
Little is known about their function and the architectural transitions of the pre-ribosomal …

Kinetoplastids are unicellular eukaryotic parasites responsible for such human pathologies
as Chagas disease, slee** sickness, and leishmaniasis. They have a single large …

The mammalian mitochondrial ribosome (mitoribosome) and its associated translational
factors have evolved to accommodate greater participation of proteins in mitochondrial …

Mammalian mitochondrial ribosomes are unique molecular machines that translate 11
leaderless mRNAs; however, it is not clear how mitoribosomes initiate translation, since …

Ribosome biogenesis requires numerous trans-acting factors, some of which are deeply
conserved. In Bacteria, the endoribonuclease YbeY is believed to be involved in 16S rRNA …