Sleep is characterized by synchronized events in billions of synaptically coupled neurons in
thalamocortical systems. The activation of a series of neuromodulatory transmitter systems …

In order to model neuronal behavior or to interpret the results of modeling studies,
neuroscientists must call upon methods of nonlinear dynamics. This book offers an …

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels comprise a small
subfamily of proteins within the superfamily of pore-loop cation channels. In mammals, the …

The vestibular system provides the brain with sensory signals about three-dimensional head
rotations and translations. These signals are important for postural and oculomotor control …

A key element of the European Union's Human Brain Project (HBP) and other large-scale
brain research projects is the simulation of large-scale model networks of neurons. Here, we …

The physiological structure of the brain and the morphology of its neurons result from
selective pressure, the nervous system must be energy efficient. In this paper, a two …

▪ Abstract Thalamocortical activity exhibits two distinct states:(a) synchronized rhythmic
activity in the form of delta, spindle, and other slow waves during EEG-synchronized sleep …

Deep brain stimulation (DBS) is an effective therapy for medically refractory movement
disorders. However, fundamental questions remain about the effects of DBS on neurons …

Many of our daily activities, such as riding a bike to work or reading a book in a noisy cafe,
and highly skilled activities, such as a professional playing a tennis match or a violin …

Sensory perception depends on neocortical computations that contextually adjust sensory
signals in different internal and environmental contexts. Neocortical layer 1 (L1) is the main …