Stroke is a leading cause of morbidity and mortality worldwide, and consists of two types,
ischemic and hemorrhagic. Currently, there is no effective treatment to increase the survival …

Chemokines, small pro-inflammatory chemoattractant cytokines that bind to specific G-
protein-coupled seven-span transmembrane receptors, are major regulators of cell …

Chemokines are small molecules called “chemotactic cytokines” and regulate many
processes like leukocyte trafficking, homing of immune cells, maturation, cytoskeletal …

Background Myocardial ischemia–reperfusion injury (MIRI) is a major obstacle in the
treatment of ischemic heart disease. Recent studies have shown that exosomes—small …

Neurodegenerative processes encompass a large variety of diseases with different
pathological patterns and clinical features, such as Alzheimer's and Parkinson's diseases …

One of the more important recent advances in neuroscience research is the understanding
that there is extensive communication between the immune system and the central nervous …

Background: Pancreatic cancer cells are highly resistant to drug therapy; however,
underlying causes remain largely unknown. We hypothesised that the activation of CXCL12 …

In the last decade, tremendous progress has been made in understanding the biology of
microglia–ie the fascinating immigrated resident immune cell population of the central …

Background and Purpose—Inflammatory response plays a critical role in propagating tissue
damage after focal cerebral ischemia. CXCL12 is a key chemokine for leukocyte recruitment …

Accumulating evidence suggests that the pathophysiology of depression might be
associated with neuroinflammation, which could be attenuated by pharmacological …