Aging is a major risk factor in the development of chronic diseases affecting various tissues
including the cardiovascular system, muscle and bones. Age-related diseases are a …

Background Both genetic background and diet are important determinants of cardiovascular
diseases (CVD). Understanding gene-diet interactions could help improve CVD prevention …

Background The comorbidity of major depressive disorder (MDD) and stroke are common in
clinic. There is a growing body of evidence suggesting a bi-directional relationship between …

Background: Carotid intima-media thickness (cIMT) has been associated with an elevated
risk of ischemic stroke (IS) in several studies, but the results are inconsistent. We …

Introduction Considering the emergence of the concept of personalized nutrition in recent
years and its importance in the treatment of diseases, the purpose of this study was to …

Background Paraoxonases (PONs) are a family of orphan enzymes with multiple functions,
including anti-inflammatory, antioxidative, antiatherogenic activities. Studies have suggested …

Purpose To investigate associations for polymorphisms in β-carotene 9′, 10′-oxygenase
(BCO2, rs10431036 and rs11214109), proprotein convertase subtilisin kexin type 9 (PCSK9 …

Background: PON1 is an High Density Lipoprotein (HDL)-associated esterase. Two common
polymorphisms in the PON1 gene, Q192R and L55M substitutions, determine the inter …

Cerebrovascular accidents (CVAs) are vascular multifactorial, multigenic ailments with
intricate genetic, environmental risk influences. The present study aimed to establish …

Gene–gene interaction (G× G) is thought to fill the gap between the estimated heritability of
complex diseases and the limited genetic proportion explained by identified single …