Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …

Integrin receptors are the main molecular link between cells and the extracellular matrix
(ECM) as well as mediating cell–cell interactions. Integrin–ECM binding triggers the …

The immune system plays a pivotal role in maintaining physiological homeostasis and
influencing disease processes. Dysregulated immune responses drive chronic inflammation …

This work introduces NeoMag, a system designed to enhance cell mechanics assays in
substrate deformation studies. NeoMag uses multidomain magneto‐active materials to …

The interactions between cells and their surrounding extracellular matrix (ECM) are dynamic
and play critical roles in cell migration during development, health, and diseases. Recent …

Cell migration is controlled by the coordinated action of cell adhesion, cytoskeletal
dynamics, contractility and cell extrinsic cues. Integrins are the main adhesion receptors to …

With the advent of mechanobiology, cell shape and forces have emerged as essential
elements of cell behavior and fate, in addition to biochemical factors such as growth factors …

Tendon injury is a common motor system disease, impairing joint mobility, and lowering
quality of life. Once damaged, tendon has a limited capacity for regeneration. Clinically …

The extracellular matrix (ECM) of solid tumors impacts the antitumor activities of CD8+ T and
natural killer (NK) cells in a variety of ways. Cell motility is restricted by the tumor ECM which …

Rho GTPases play a key role in the spatio-temporal coordination of cytoskeletal dynamics
during cell migration. Here, we directly investigate crosstalk between the major Rho …