Biomaterials for intervertebral disc regeneration and repair

RD Bowles, LA Setton - Biomaterials, 2017 - Elsevier
The intervertebral disc contributes to motion, weight bearing, and flexibility of the spine, but
is susceptible to damage and morphological changes that contribute to pathology with age …

Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its …

JC Iatridis, SB Nicoll, AJ Michalek, BA Walter… - The spine journal, 2013 - Elsevier
BACKGROUND CONTEXT: Degeneration and injuries of the intervertebral disc (IVD) result
in large alterations in biomechanical behaviors. Repair strategies using biomaterials can be …

[HTML][HTML] Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the Wakayama Spine Study

M Teraguchi, N Yoshimura, H Hashizume… - Osteoarthritis and …, 2014 - Elsevier
Objectives The purposes of this study were to investigate the prevalence and distribution of
intervertebral disc degeneration (DD) over the entire spine using magnetic resonance …

Modified Pfirrmann grading system for lumbar intervertebral disc degeneration

JF Griffith, YXJ Wang, GE Antonio, KC Choi, A Yu… - Spine, 2007 - journals.lww.com
Study Design. A reliability study was conducted. Objective. To modify a grading system for
lumbar disc degeneration and to test the reliability of this modified grading system. Summary …

Diagnostic imaging in intervertebral disc disease

RC Da Costa, S De Decker, MJ Lewis… - Frontiers in veterinary …, 2020 - frontiersin.org
Imaging is integral in the diagnosis of canine intervertebral disc disease (IVDD) and in
differentiating subtypes of intervertebral disc herniation (IVDH). These include intervertebral …

A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status

D Samartzis, J Karppinen, F Mok, DYT Fong, KDK Luk… - JBJS, 2011 - journals.lww.com
Background: Little is known regarding juvenile disc degeneration in individuals with normal
spinal alignment. Consequently, the purpose of this study was to assess the prevalence …

Factors associated with lumbar intervertebral disc degeneration in the elderly

M Hangai, K Kaneoka, S Kuno, S Hinotsu, M Sakane… - The spine journal, 2008 - Elsevier
BACKGROUND CONTEXT: Lumbar intervertebral disc degeneration (DD) precedes
degenerative diseases of the lumbar spine. Various factors in addition to normal aging are …

2004 Young Investigator Award Winner: vertebral endplate marrow contact channel occlusions and intervertebral disc degeneration

LM Benneker, PF Heini, M Alini, SE Anderson, K Ito - Spine, 2005 - journals.lww.com
Study Design. Intervertebral disc degeneration was evaluated by morphologic appearance,
magnetic resonance imaging, and by biochemical matrix composition. Caliber and …

Innervation of pathologies in the lumbar vertebral end plate and intervertebral disc

AJ Fields, EC Liebenberg, JC Lotz - The Spine Journal, 2014 - Elsevier
Background context Magnetic resonance imaging (MRI) has limited diagnostic value for
chronic low back pain because of the unclear relationship between any anatomic …

Influence of single-level lumbar degenerative disc disease on the behavior of the adjacent segments—a finite element model study

LM Ruberté, RN Natarajan, GBJ Andersson - Journal of biomechanics, 2009 - Elsevier
The current study investigated mechanical predictors for the development of adjacent disc
degeneration. A 3-D finite element model of a lumbar spine was modified to simulate two …