A review of cyclic olefin copolymer applications in microfluidics and microdevices

A Agha, W Waheed, N Alamoodi… - Macromolecular …, 2022 - Wiley Online Library
Cyclic olefin copolymers (COC) are amorphous, transparent thermoplastics composed of
cyclic olefin monomers (norbornene) and linear olefins (ethene). They are increasingly …

Advances in microfluidics‐based assisted reproductive technology: From sperm sorter to reproductive system‐on‐a‐chip

N Kashaninejad, MJA Shiddiky… - Advanced …, 2018 - Wiley Online Library
The fields of assisted reproductive technology (ART) and in vitro fertilization (IVF) have
progressed rapidly, yet still need further improvements. Microfluidic technology can …

IVF-on-a-chip: recent advances in microfluidics technology for in vitro fertilization

L Weng - SLAS TECHNOLOGY: Translating Life Sciences …, 2019 - journals.sagepub.com
In vitro fertilization (IVF) has been one of the most exciting modern medical technologies. It
has transformed the landscape of human infertility treatment. However, current IVF …

A microfluidic organotypic device for culture of mammalian intestines ex vivo

A Richardson, LA Schwerdtfeger, D Eaton… - Analytical …, 2020 - pubs.rsc.org
The physiological characteristics of the gastrointestinal (GI) tract are diverse and include
rapid rates of epithelial turnover, complex nervous and immune systems, a thick mucus …

Investigating and modelling an engineered millifluidic in vitro oocyte maturation system reproducing the physiological ovary environment in the sheep model

A Mastrorocco, L Cacopardo, L Temerario, NA Martino… - Cells, 2022 - mdpi.com
In conventional assisted reproductive technologies (ARTs), oocytes are in vitro cultured in
static conditions. Instead, dynamic systems could better mimic the physiological in vivo …

Fighting like cats and dogs: challenges in domestic carnivore oocyte development and promises of innovative culture systems

M Colombo, IM Alkali, S Prochowska, GC Luvoni - Animals, 2021 - mdpi.com
Simple Summary In assisted reproduction, in vitro embryo production is the generation of
embryos from isolated gametes in an equipped laboratory. This procedure is commonly …

Electrically-driven handling of gametes and embryos: taking a step towards the future of ARTs

A Karcz, A Van Soom, K Smits, R Verplancke… - Lab on a Chip, 2022 - pubs.rsc.org
Electrical stimulation of gametes and embryos and on-chip manipulation of microdroplets of
culture medium serve as promising tools for assisted reproductive technologies (ARTs) …

[HTML][HTML] Improving assay feasibility and biocompatibility of 3D cyclic olefin copolymer microwells by superhydrophilic modification via ultrasonic spray deposition of …

A Jagannath, M Yu, J Li, N Zhang, MD Gilchrist - Biomaterials Advances, 2024 - Elsevier
Sample partitioning is a crucial step towards digitization of biological assays on polymer
microfluidic platforms. However, effective liquid filling into microwells and long-term …

Reconstruction of in vivo-like in vitro model: enabling technologies of microfluidic systems for dynamic biochemical/mechanical stimuli

SM Park, S Eom, H Hong, J Yoon, SJ Lee… - Microelectronic …, 2019 - Elsevier
In the past two decades, significant advances have been achieved for the emergence and
rapid growth of in vivo-like in vitro cell culture platforms, especially organ-on-a-chip, which …

Opportunities involving microfluidics and 3D culture systems to the in vitro embryo production

MAMM Ferraz, GA Ferronato - Animal Reproduction, 2023 - SciELO Brasil
Traditional methods of gamete handling, fertilization, and embryo culture often face
limitations in efficiency, consistency, and the ability to closely mimic in vivo conditions. This …