A review of cyclic olefin copolymer applications in microfluidics and microdevices
Cyclic olefin copolymers (COC) are amorphous, transparent thermoplastics composed of
cyclic olefin monomers (norbornene) and linear olefins (ethene). They are increasingly …
cyclic olefin monomers (norbornene) and linear olefins (ethene). They are increasingly …
Advances in microfluidics‐based assisted reproductive technology: From sperm sorter to reproductive system‐on‐a‐chip
The fields of assisted reproductive technology (ART) and in vitro fertilization (IVF) have
progressed rapidly, yet still need further improvements. Microfluidic technology can …
progressed rapidly, yet still need further improvements. Microfluidic technology can …
IVF-on-a-chip: recent advances in microfluidics technology for in vitro fertilization
L Weng - SLAS TECHNOLOGY: Translating Life Sciences …, 2019 - journals.sagepub.com
In vitro fertilization (IVF) has been one of the most exciting modern medical technologies. It
has transformed the landscape of human infertility treatment. However, current IVF …
has transformed the landscape of human infertility treatment. However, current IVF …
A microfluidic organotypic device for culture of mammalian intestines ex vivo
A Richardson, LA Schwerdtfeger, D Eaton… - Analytical …, 2020 - pubs.rsc.org
The physiological characteristics of the gastrointestinal (GI) tract are diverse and include
rapid rates of epithelial turnover, complex nervous and immune systems, a thick mucus …
rapid rates of epithelial turnover, complex nervous and immune systems, a thick mucus …
Investigating and modelling an engineered millifluidic in vitro oocyte maturation system reproducing the physiological ovary environment in the sheep model
A Mastrorocco, L Cacopardo, L Temerario, NA Martino… - Cells, 2022 - mdpi.com
In conventional assisted reproductive technologies (ARTs), oocytes are in vitro cultured in
static conditions. Instead, dynamic systems could better mimic the physiological in vivo …
static conditions. Instead, dynamic systems could better mimic the physiological in vivo …
Fighting like cats and dogs: challenges in domestic carnivore oocyte development and promises of innovative culture systems
M Colombo, IM Alkali, S Prochowska, GC Luvoni - Animals, 2021 - mdpi.com
Simple Summary In assisted reproduction, in vitro embryo production is the generation of
embryos from isolated gametes in an equipped laboratory. This procedure is commonly …
embryos from isolated gametes in an equipped laboratory. This procedure is commonly …
Electrically-driven handling of gametes and embryos: taking a step towards the future of ARTs
Electrical stimulation of gametes and embryos and on-chip manipulation of microdroplets of
culture medium serve as promising tools for assisted reproductive technologies (ARTs) …
culture medium serve as promising tools for assisted reproductive technologies (ARTs) …
[HTML][HTML] Improving assay feasibility and biocompatibility of 3D cyclic olefin copolymer microwells by superhydrophilic modification via ultrasonic spray deposition of …
Sample partitioning is a crucial step towards digitization of biological assays on polymer
microfluidic platforms. However, effective liquid filling into microwells and long-term …
microfluidic platforms. However, effective liquid filling into microwells and long-term …
Reconstruction of in vivo-like in vitro model: enabling technologies of microfluidic systems for dynamic biochemical/mechanical stimuli
In the past two decades, significant advances have been achieved for the emergence and
rapid growth of in vivo-like in vitro cell culture platforms, especially organ-on-a-chip, which …
rapid growth of in vivo-like in vitro cell culture platforms, especially organ-on-a-chip, which …
Opportunities involving microfluidics and 3D culture systems to the in vitro embryo production
Traditional methods of gamete handling, fertilization, and embryo culture often face
limitations in efficiency, consistency, and the ability to closely mimic in vivo conditions. This …
limitations in efficiency, consistency, and the ability to closely mimic in vivo conditions. This …