Multi-criteria optimization and decision-making in radiotherapy

S Breedveld, D Craft, R Van Haveren… - European Journal of …, 2019 - Elsevier
Radiotherapy (radiation therapy) is one of the main treatments for cancer. The aim is to
deliver a prescribed radiation dose to the tumor, while kee** the unavoidable dose to the …

Conditional value‐at‐risk beyond finance: a survey

C Filippi, G Guastaroba… - … in Operational Research, 2020 - Wiley Online Library
A large number of problems involve making decisions in an uncertain environment and,
hence, with unknown outcomes. Optimization models aimed at controlling the trade‐off …

4π non-coplanar liver SBRT: a novel delivery technique

P Dong, P Lee, D Ruan, T Long, E Romeijn… - International Journal of …, 2013 - Elsevier
PURPOSE: To improve the quality of liver stereotactic body radiation therapy (SBRT)
treatments, a novel 4π framework was developed with accompanying algorithms to optimize …

4π noncoplanar stereotactic body radiation therapy for centrally located or larger lung tumors

P Dong, P Lee, D Ruan, T Long, E Romeijn… - International Journal of …, 2013 - Elsevier
PURPOSE: To investigate the dosimetric improvements in stereotactic body radiation
therapy for patients with larger or central lung tumors using a highly noncoplanar 4π …

A large-scale combinatorial many-objective evolutionary algorithm for intensity-modulated radiotherapy planning

Y Tian, Y Feng, C Wang, R Cao… - IEEE transactions on …, 2022 - ieeexplore.ieee.org
Intensity-modulated radiotherapy (IMRT) is one of the most popular techniques for cancer
treatment. However, existing IMRT planning methods can only generate one solution at a …

Integrated beam orientation and scanning‐spot optimization in intensity‐modulated proton therapy for brain and unilateral head and neck tumors

W Gu, D O'Connor, D Nguyen, VY Yu, D Ruan… - Medical …, 2018 - Wiley Online Library
Purpose Intensity‐Modulated Proton Therapy (IMPT) is the state‐of‐the‐art method of
delivering proton radiotherapy. Previous research has been mainly focused on optimization …

Optimization approaches to volumetric modulated arc therapy planning

J Unkelbach, T Bortfeld, D Craft, M Alber… - Medical …, 2015 - Wiley Online Library
Volumetric modulated arc therapy (VMAT) has found widespread clinical application in
recent years. A large number of treatment planning studies have evaluated the potential for …

Treatment planning comparison of IMPT, VMAT and 4π radiotherapy for prostate cases

A Tran, J Zhang, K Woods, V Yu, D Nguyen… - Radiation …, 2017 - Springer
Background Intensity-modulated proton therapy (IMPT), non-coplanar 4π intensity-
modulated radiation therapy (IMRT), and volumetric-modulated arc therapy (VMAT) …

Beam angle optimization for proton therapy via group‐sparsity based angle generation method

H Shen, G Zhang, Y Lin, RL Rotondo, Y Long… - Medical …, 2023 - Wiley Online Library
Background In treatment planning, beam angle optimization (BAO) refers to the selection of
a subset with a given number of beam angles from all available angles that provides the …

GPU-based ultrafast IMRT plan optimization

C Men, X Gu, D Choi, A Majumdar… - Physics in Medicine …, 2009 - iopscience.iop.org
The widespread adoption of on-board volumetric imaging in cancer radiotherapy has
stimulated research efforts to develop online adaptive radiotherapy techniques to handle the …