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Using clusterProfiler to characterize multiomics data
With the advent of multiomics, software capable of multidimensional enrichment analysis
has become increasingly crucial for uncovering gene set variations in biological processes …
has become increasingly crucial for uncovering gene set variations in biological processes …
The evolution of single-cell RNA sequencing technology and application: progress and perspectives
S Wang, ST Sun, XY Zhang, HR Ding, Y Yuan… - International journal of …, 2023 - mdpi.com
As an emerging sequencing technology, single-cell RNA sequencing (scRNA-Seq) has
become a powerful tool for describing cell subpopulation classification and cell …
become a powerful tool for describing cell subpopulation classification and cell …
[HTML][HTML] Immunostimulatory effects of thermal ablation: Challenges and future prospects
P Liu, Z Wei, X Ye - Journal of Cancer Research and …, 2024 - journals.lww.com
This literature explores the immunostimulatory effects of thermal ablation in the tumor
microenvironment, elucidating the mechanisms such as immunogenic cell death, tumor …
microenvironment, elucidating the mechanisms such as immunogenic cell death, tumor …
[HTML][HTML] Photothermal therapy improves the efficacy of topical immunotherapy against melanoma
Background Melanoma is an aggressive cancer with poor response to traditional therapies.
A combination of photothermal therapy and topical immunotherapy may enhance …
A combination of photothermal therapy and topical immunotherapy may enhance …
[HTML][HTML] Localized ablative immunotherapy enhances antitumor immunity by modulating the transcriptome of tumor-infiltrating Gamma delta T cells
Gamma delta T cells (γδT cells) play crucial roles in the immune response against tumors,
yet their functional dynamics under different cancer therapies remain poorly understood …
yet their functional dynamics under different cancer therapies remain poorly understood …
[HTML][HTML] N-dihydrogalactochitosan serves as an effective mucosal adjuvant for intranasal vaccine in combination with recombinant viral proteins against respiratory …
Mucosal vaccinations for respiratory pathogens provide effective protection as they stimulate
localized cellular and humoral immunities at the site of infection. Currently, the major …
localized cellular and humoral immunities at the site of infection. Currently, the major …
Immune modulations of the tumor microenvironment in response to phototherapy
TI Valerio, CL Furrer, N Sadeghipour… - Journal of innovative …, 2023 - World Scientific
The tumor microenvironment (TME) promotes pro-tumor and anti-inflammatory metabolisms
and suppresses the host immune system. It prevents immune cells from fighting against …
and suppresses the host immune system. It prevents immune cells from fighting against …
N‐Dihydrogalactochitosan Drives Conventional and Alternative Activations of STING to Synergize Type I IFN and IL‐1β Productions for Antitumor Immunity.
AR Hoover, K Liu, C Furrer, SSK Lam… - Advanced Functional …, 2024 - Wiley Online Library
N‐dihydrogalactochitosan (GC) is an immune stimulant/adjuvant. Synthesized from chitosan
and galactose, GC is a new chemical entity that significantly enhances the immune …
and galactose, GC is a new chemical entity that significantly enhances the immune …
Amino acids and their roles in tumor immunotherapy of breast cancer
H **a, J Zhu, Z Zheng, P **ao, X Yu… - The Journal of Gene …, 2024 - Wiley Online Library
Breast cancer is the most commonly diagnosed cancer among women. The primary
treatment options include surgery, radiotherapy, chemotherapy, targeted therapy and …
treatment options include surgery, radiotherapy, chemotherapy, targeted therapy and …
Localized ablative immunotherapy drives de novo CD8+ T-cell responses to poorly immunogenic tumors
AR Hoover, S Kaabinejadian, JR Krawic… - Journal for …, 2022 - pmc.ncbi.nlm.nih.gov
Background Localized ablative immunotherapies hold great promise in stimulating antitumor
immunity to treat metastatic and poorly immunogenic tumors. Tumor ablation is well known …
immunity to treat metastatic and poorly immunogenic tumors. Tumor ablation is well known …