Synthesis of Sulfilimines Enabled by Copper-Catalyzed S-Arylation of Sulfenamides

Q Liang, LA Wells, K Han, S Chen… - Journal of the …, 2023 - ACS Publications
Herein, an unprecedented synthetic route to sulfilimines via a copper-catalyzed Chan–Lam-
type coupling of sulfenamides is presented. A key to success in this novel transformation is …

Enantioselective arylation of sulfenamides to access sulfilimines enabled by palladium catalysis

Y Yuan, Y Han, Z Zhang, S Sun, K Wu… - Angewandte Chemie …, 2024 - Wiley Online Library
Sulfur‐containing functional groups have garnered considerable attention due to their
common occurrence in ligands, pharmaceuticals, and insecticides. Nevertheless …

Ethyl ester/acyl hydrazide-based aromatic sulfonamides: facile synthesis, structural characterization, electrochemical measurements and theoretical studies as …

MA Bedair, AM Abuelela, M Alshareef, M Owda… - RSC …, 2023 - pubs.rsc.org
In this research paper, aromatic sulfonamide-derived ethyl ester (p-TSAE) and its acyl
hydrazide (p-TSAH) were directly synthesized, characterized, and employed for the first time …

Modular synthesis of functional libraries by accelerated SuFEx click chemistry

JA Homer, RA Koelln, AS Barrow, TL Gialelis… - Chemical …, 2024 - pubs.rsc.org
Accelerated SuFEx Click Chemistry (ASCC) is a powerful method for coupling aryl and alkyl
alcohols with SuFEx-compatible functional groups. With its hallmark favorable kinetics and …

Copper-catalyzed synthesis of functionalized aryl sulfonamides from sodium sulfinates in green solvents

LY Lam, KH Chan, C Ma - The Journal of Organic Chemistry, 2022 - ACS Publications
Functionalized aryl sulfonamides are important building blocks in the pharmaceutical
industry. A one-step synthesis catalyzed by a copper salt was developed using stable solid …

Bypassing Sulfonyl Halides: Synthesis of Sulfonamides from Other Sulfur‐Containing Building Blocks

B Sosunovych, BV Vashchenko… - The Chemical …, 2024 - Wiley Online Library
This review disclosed synthetic approaches to sulfonyl amides from non‐sulfonyl
halogenated precursors. Known methods were systematized into groups and subgroups …

Photo‐Triggered Synthesis of Sulfonamides in a Sustainable Solvent via Electron Donor‐Acceptor Complex

A Kamal, HK Singh, SK Maury… - Asian Journal of …, 2023 - Wiley Online Library
A visible‐light‐triggered synthesis of sulfonamide was developed via an electron donor‐
acceptor (EDA) complex in the more environmentally friendly green solvent 2 …

A General Amino–(Hetero)arylation of Simple Olefins with (Hetero)aryl Sulfonamides Enabled by an N-Triazinyl Group

JL Barney, AJ Wolfram, R Litvak, ED Nacsa - ACS Catalysis, 2025 - ACS Publications
(Hetero) arylethylamines are privileged substructures in pharmaceuticals, agrochemicals,
and other bioactive compounds. In principle, the amino–(hetero) arylation of olefins …

A combined experimental and computational study of ligand-controlled Chan-Lam coupling of sulfenamides

K Han, H Liu, ME Rotella, Z Xu, L Tao, S Chen… - Nature …, 2024 - nature.com
The unique features of the sulfenamides' S (II)-N bond lead to interesting stereochemical
properties and significant industrial functions. Here we present a chemoselective Chan–Lam …

Thiosuccinimide enabled S–N bond formation to access N-sulfenylated sulfonamide derivatives with synthetic diversity

P Wang, S Li, H Wen, Y Lei, S Huang… - Organic & …, 2024 - pubs.rsc.org
A thiosuccinimide enabled S–N cross-coupling strategy has been established for the
intermolecular N-sulfenylation of clinically approved sulfa drugs under additive-free …