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MiRNA-based therapies for lung cancer: opportunities and challenges?
H Yang, Y Liu, L Chen, J Zhao, M Guo, X Zhao, Z Wen… - Biomolecules, 2023 - mdpi.com
Lung cancer is a commonly diagnosed cancer and the leading cause of cancer-related
deaths, posing a serious health risk. Despite new advances in immune checkpoint and …
deaths, posing a serious health risk. Despite new advances in immune checkpoint and …
Cell death pathways of particulate matter toxicity
Humans are exposed to various complex mixtures of particulate matter (PM) from different
sources. Long-term exposure to high levels of these particulates has been linked to a …
sources. Long-term exposure to high levels of these particulates has been linked to a …
Adiponectin stimulates autophagy and reduces oxidative stress to enhance insulin sensitivity during high-fat diet feeding in mice
Y Liu, R Palanivel, E Rai, M Park, TV Gabor… - Diabetes, 2015 - diabetesjournals.org
Numerous studies have characterized the antidiabetic effects of adiponectin, yet the precise
cellular mechanisms in skeletal muscle, in particular, changes in autophagy, require further …
cellular mechanisms in skeletal muscle, in particular, changes in autophagy, require further …
Cell death and inflammatory bowel diseases: apoptosis, necrosis, and autophagy in the intestinal epithelium
Cell death mechanisms have been associated with the development of inflammatory bowel
diseases in humans and mice. Recent studies suggested that a complex crosstalk between …
diseases in humans and mice. Recent studies suggested that a complex crosstalk between …
Sodium butyrate inhibits migration and induces AMPK‐mTOR pathway‐dependent autophagy and ROS‐mediated apoptosis via the miR‐139‐5p/Bmi‐1 axis in …
F Wang, H Wu, M Fan, R Yu, Y Zhang, J Liu… - The FASEB …, 2020 - Wiley Online Library
Bladder cancer is one of the most frequently occurring malignant tumors in the urinary
system. Sodium butyrate (NaB) is a histone deacetylase inhibitor and exerts remarkable …
system. Sodium butyrate (NaB) is a histone deacetylase inhibitor and exerts remarkable …
Hydrogen sulfide and autophagy: a double edged sword
D Wu, H Wang, T Teng, S Duan, A Ji, Y Li - Pharmacological research, 2018 - Elsevier
Hydrogen sulfide (H 2 S) has been considered the third gaseous signaling molecule that
plays important roles in a wide range of physiological and pathological conditions. However …
plays important roles in a wide range of physiological and pathological conditions. However …
Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas
Oral squamous cell carcinomas (OSCC) and esophageal squamous cell carcinomas
(ESCC) exhibit a survival rate of less than 60% and 40%, respectively. Late‐stage diagnosis …
(ESCC) exhibit a survival rate of less than 60% and 40%, respectively. Late‐stage diagnosis …
Mechanisms underlying curcumin-induced neuroprotection in cerebral ischemia
F Fan, M Lei - Frontiers in Pharmacology, 2022 - frontiersin.org
Ischemic stroke is the leading cause of death and disability worldwide, and restoring the
blood flow to ischemic brain tissues is currently the main therapeutic strategy. However …
blood flow to ischemic brain tissues is currently the main therapeutic strategy. However …
A double negative feedback loop between mTORC1 and AMPK kinases guarantees precise autophagy induction upon cellular stress
Cellular homeostasis is controlled by an evolutionary conserved cellular digestive process
called autophagy. This mechanism is tightly regulated by the two sensor elements called …
called autophagy. This mechanism is tightly regulated by the two sensor elements called …
Apoptotic cell death induced by resveratrol is partially mediated by the autophagy pathway in human ovarian cancer cells
F Lang, Z Qin, F Li, H Zhang, Z Fang, E Hao - PloS one, 2015 - journals.plos.org
Resveratrol (trans-3, 4, 5'–trihydroxystilbene) is an active compound in food, such as red
grapes, peanuts, and berries. Resveratrol exhibits an anticancer effect on various human …
grapes, peanuts, and berries. Resveratrol exhibits an anticancer effect on various human …