[HTML][HTML] Modern isolation and separation techniques for extracellular vesicles

T Liangsupree, E Multia, ML Riekkola - Journal of Chromatography A, 2021 - Elsevier
Extracellular vesicles (EVs) are heterogenous membrane-bound vesicles released from
various origins. EVs play a crucial role in cellular communication and mediate several …

Current challenges and future directions for engineering extracellular vesicles for heart, lung, blood and sleep diseases

G Li, T Chen, J Dahlman… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) carry diverse bioactive components including nucleic acids,
proteins, lipids and metabolites that play versatile roles in intercellular and interorgan …

[HTML][HTML] Manufacturing therapeutic exosomes: from bench to industry

SH Ahn, SW Ryu, H Choi, S You, J Park, C Choi - Molecules and cells, 2022 - Elsevier
Exosome, a type of nanoparticles also known as small extracellular vesicles are gaining
attention as novel therapeutics for various diseases because of their ability to deliver genetic …

The landscape of biomimetic nanovesicles in brain diseases

Q You, F Liang, G Wu, F Cao, J Liu, Z He… - Advanced …, 2024 - Wiley Online Library
Brain diseases, such as brain tumors, neurodegenerative diseases, cerebrovascular
diseases, and brain injuries, are caused by various pathophysiological changes, which pose …

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

SM Davidson, CM Boulanger, E Aikawa… - Cardiovascular …, 2023 - academic.oup.com
Extracellular vesicles (EVs) are nanosized vesicles with a lipid bilayer that are released from
cells of the cardiovascular system, and are considered important mediators of intercellular …

A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs

B Bogaert, F Sauvage, R Guagliardo, C Muntean… - Journal of Controlled …, 2022 - Elsevier
Since the recent clinical approval of siRNA-based drugs and COVID-19 mRNA vaccines, the
potential of RNA therapeutics for patient healthcare has become widely accepted. Lipid …

Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application

Q Yang, S Li, H Ou, Y Zhang, G Zhu, S Li… - Journal of …, 2024 - Springer
Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …

Engineered extracellular vesicles: tailored-made nanomaterials for medical applications

K Man, MY Brunet, MC Jones, SC Cox - Nanomaterials, 2020 - mdpi.com
Extracellular vesicles (EVs) are emerging as promising nanoscale therapeutics due to their
intrinsic role as mediators of intercellular communication, regulating tissue development and …

Technological aspects of manufacturing and analytical control of biological nanoparticles

S Brezgin, A Parodi, A Kostyusheva… - Biotechnology …, 2023 - Elsevier
Extracellular vesicles (EVs) are cell-derived biological nanoparticles that gained great
interest for drug delivery. EVs have numerous advantages compared to synthetic …

Extruded mesenchymal stem cell nanovesicles are equally potent to natural extracellular vesicles in cardiac repair

X Wang, S Hu, J Li, D Zhu, Z Wang… - … applied materials & …, 2021 - ACS Publications
Mesenchymal stem cells (MSCs) repair injured tissues mainly through their paracrine
actions. One of the important paracrine components of MSC secretomes is the extracellular …