Cerebrospinal fluid microRNAs as potential biomarkers in Alzheimer's disease

A Noor Eddin, K Hamsho, G Adi… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is the leading form of dementia worldwide, but its early detection
and diagnosis remain a challenge. MicroRNAs (miRNAs) are a group of small endogenous …

[HTML][HTML] Insights into the Role of microRNAs as Clinical Tools for Diagnosis, Prognosis, and as Therapeutic Targets in Alzheimer's Disease

N Puranik, M Song - International Journal of Molecular Sciences, 2024 - mdpi.com
Neurodegenerative diseases (NDDs) are a diverse group of neurological disorders
characterized by alterations in the structure and function of the central nervous system …

Triptolide improves Alzheimer's disease by regulating the NF‑κB signaling pathway through the lncRNA NEAT1/microRNA 361‑3p/TRAF2 axis

L Zhou, X Huang, H Li, J Wang… - Experimental and …, 2023 - spandidos-publications.com
Alzheimer's disease (AD) is the most common type of dementia and is a serious social and
medical problem threatening human health. The present study investigated the effect and …

[HTML][HTML] Artificial Intelligence-Assisted Comparative Analysis of the Overlap** Molecular Pathophysiology of Alzheimer's Disease, Amyotrophic Lateral Sclerosis …

Z Wei, MR Iyer, B Zhao, J Deng, CS Mitchell - International Journal of …, 2024 - mdpi.com
The overlap** molecular pathophysiology of Alzheimer's Disease (AD), Amyotrophic
Lateral Sclerosis (ALS), and Frontotemporal Dementia (FTD) was analyzed using …

MHMDA:“Similarity-Association-Similarity” Metapaths and Heterogeneous-Hyper Network Learning for MiRNA-Disease Association Prediction

R Li, Q Ning, Y aomiao Zhao, S Guo… - IEEE Transactions on …, 2025 - ieeexplore.ieee.org
In recent years, microRNA (miRNA) has been recognized as crucial in the progression of
human diseases. However, existing computational methods for identifying miRNAdisease …

The Clinical Significance and the Potential Regulatory Mechanism of the LncRNA OIP5-AS1 in Paediatric Severe Community-Acquired Pneumonia Blood Through the …

J Lu, Q Ren, W Qi, N Yang, Y He - Immunological Investigations, 2024 - Taylor & Francis
Background This study aimed to elucidate the clinical significance and regulatory
mechanism of the long non-coding RNA OIP5-AS1 in severe community-acquired …

Sleep and diurnal alternative polyadenylation sites associated with human APA-linked brain disorders

CC Flores, NA Pasetto, H Wang, AG Dimitrov… - Npj Biological Timing …, 2024 - nature.com
Disruption of sleep and circadian rhythms are a comorbid feature of many pathologies, and
can negatively influence many health conditions, including neurodegenerative disease …

[HTML][HTML] Biomarkers in neurodegenerative diseases: a broad overview

S Selvam, V Ayyavoo - Exploration of Neuroprotective Therapy, 2024 - explorationpub.com
Degeneration and dysfunction of neurons in the brain are hallmarks of neurodegenerative
diseases. Over the past decades, significant efforts have been devoted to the development …