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Magnetic resonance spectroscopy studies of glutamate-related abnormalities in mood disorders
In mood disorders, there is growing evidence for glutamatergic abnormalities derived from
peripheral measures of glutamatergic metabolites in patients, postmortem studies on …
peripheral measures of glutamatergic metabolites in patients, postmortem studies on …
Ammonia toxicity to the brain
Hyperammonemia can be caused by various acquired or inherited disorders such as urea
cycle defects. The brain is much more susceptible to the deleterious effects of ammonium in …
cycle defects. The brain is much more susceptible to the deleterious effects of ammonium in …
The neurochemical profile quantified by in vivo 1H NMR spectroscopy
Proton NMR spectroscopy is emerging from translational and preclinical neuroscience
research as an important tool for evidence based diagnosis and therapy monitoring. It …
research as an important tool for evidence based diagnosis and therapy monitoring. It …
Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania
BACKGROUND: At excitatory synapses, glutamate released from neurons is taken up by
glial cells and converted to glutamine, which is cycled back to neurons. Alterations in this …
glial cells and converted to glutamine, which is cycled back to neurons. Alterations in this …
Relationship among glutamine, γ-aminobutyric acid, and social cognition in autism spectrum disorders
DM Cochran, EM Sikoglu, SM Hodge… - Journal of child and …, 2015 - liebertpub.com
Objective: An imbalance of excitatory and inhibitory neurotransmission in autism spectrum
disorder (ASD) has been proposed. We compared glutamate (Glu), glutamine (Gln), and γ …
disorder (ASD) has been proposed. We compared glutamate (Glu), glutamine (Gln), and γ …
Slice‐selective FID acquisition, localized by outer volume suppression (FIDLOVS) for 1H‐MRSI of the human brain at 7 T with minimal signal loss
A Henning, A Fuchs, JB Murdoch… - NMR in Biomedicine …, 2009 - Wiley Online Library
Abstract In comparison to 1.5 and 3 T, MR spectroscopic imaging at 7 T benefits from signal‐
to‐noise ratio (SNR) gain and increased spectral resolution and should enable map** of a …
to‐noise ratio (SNR) gain and increased spectral resolution and should enable map** of a …
Rapid enhancement of glutamatergic neurotransmission in bipolar depression following treatment with riluzole
BP Brennan, JI Hudson, JE Jensen… - …, 2010 - nature.com
Glutamatergic abnormalities may underlie bipolar disorder (BD). The glutamate-modulating
drug riluzole may be efficacious in bipolar depression, but few in vivo studies have …
drug riluzole may be efficacious in bipolar depression, but few in vivo studies have …
High and ultra-high resolution metabolite map** of the human brain using 1H FID MRSI at 9.4 T
S Nassirpour, P Chang, A Henning - Neuroimage, 2018 - Elsevier
Magnetic resonance spectroscopic imaging (MRSI) is a promising technique for map**
the spatial distribution of multiple metabolites in the human brain. These metabolite maps …
the spatial distribution of multiple metabolites in the human brain. These metabolite maps …
[HTML][HTML] Emerging methods and applications of ultra-high field MR spectroscopic imaging in the human brain
Abstract Magnetic Resonance Spectroscopic Imaging (MRSI) of the brain enables insights
into the metabolic changes and fluxes in diseases such as tumors, multiple sclerosis …
into the metabolic changes and fluxes in diseases such as tumors, multiple sclerosis …
Sensitivity and source of amine‐proton exchange and amide‐proton transfer magnetic resonance imaging in cerebral ischemia
Purpose Amide‐proton transfer (APT) and amine–water proton exchange (APEX) MRI can
be viable to map pH‐decreasing ischemic regions. However, their exact contributions are …
be viable to map pH‐decreasing ischemic regions. However, their exact contributions are …