The placenta is essential for normal in utero development in mammals. In humans, defective
placental formation underpins common pregnancy disorders such as pre-eclampsia and …

The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

Leptin is now considered an important signalling molecule of the reproductive system, as it
regulates the production of gonadotrophins, the blastocyst formation and implantation, the …

Controversy surrounds reports describing the derivation of human trophoblast cells from
placentas and embryonic stem cells (ESC), partly due to the difficulty in identifying markers …

Placentation is a reproductive adaptation that permits fetal growth and development within
the protected confines of the female reproductive tract. Through this important role, the …

Given the immense antigenic load present in the microbiome, we hypothesized that
microbiota mimotopes can be a persistent trigger in human autoimmunity via cross-reactivity …

Background: Recurrent miscarriage (RM) affects 1%–3% of pregnancies. However, in
almost 50% of cases, the cause is unknown. Increasing evidence have shown that benzo (a) …

Problem The extravillous trophoblasts (EVT) express HLA‐C and HLA‐G, but HLA‐E and
HLA‐F are the subject of conflicting reports. In this study, we define the HLA expression …

Pandemics pose a more significant threat to pregnant women than to the nonpregnant
population and may have a detrimental effect on the well being of the fetus. We have …

In humans, the placenta provides the only fetomaternal connection and is essential for
establishing a pregnancy as well as fetal well-being. Additionally, it allows maternal …