Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Tanshinone IIA (Tan IIA) is a pharmacologically lipophilic active constituent isolated from the
roots and rhizomes of the Chinese medicinal herb Salvia miltiorrhiza Bunge (Danshen). Tan …

The search for natural and efficacious antineoplastic drugs, with minimal toxicity and side
effects, is an important part of antitumor drug research and development. Tanshinone IIA is …

Cisplatin represents one of the first‐line drugs used for non‐small‐cell lung cancer
treatment. However, considerable side effects and the emergence of drug resistance are …

Autophagy and endoplasmic reticulum (ER) stress are conserved processes that generally
promote survival, but can induce cell death when physiological thresholds are crossed. The …

Initially described as an ancient and highly conserved catabolic biofunction, autophagy
plays a significant role in disease pathogenesis and progression. As the bioactive ingredient …

Abstract Background The roots of Salvia miltiorrhiza are used in traditional Chinese
medicine (TCM) and have high medicinal value. Tanshinone IIA (Tan IIA) is the active …

Tanshinone IIA (TanIIA)-an active constituent of Salvia miltiorrhiza, a traditional Chinese
medicinal plant-is known to have blood circulation promotion and anti-tumor properties. Tan …

Tanshinone IIA (Tan-IIA) is an extract from the widely used traditional Chinese medicine
(TCM) Danshen (Salvia miltiorrhiza), and has been found to attenuate the proliferation of …

Tanshinone is a lipophilic compound that is present in traditional Chinese medicine and is
derived from the roots of Salvia miltiorrhiza (Danshen). It has been proven to be highly …