Diagnostic methods for Helicobacter pylori infection: ideals, options, and limitations

P Sabbagh, M Mohammadnia-Afrouzi… - European Journal of …, 2019 - Springer
Helicobacter pylori (H. pylori) resides in the stomach, colonizes gastric epithelium, and
causes several digestive system diseases. Several diagnostic methods utilizing invasive or …

[HTML][HTML] Old and New Aspects of H. pylori-Associated Inflammation and Gastric Cancer

AL Dincă, LE Meliț, CO Mărginean - Children, 2022 - mdpi.com
H. pylori is involved in the development of 80% of gastric cancers and 5.5% of all malignant
conditions worldwide. Its persistence within the host's stomach causes chronic inflammation …

Berberine attenuates chronic atrophic gastritis induced by MNNG and its potential mechanism

Y Tong, L Liu, R Wang, T Yang, J Wen, S Wei… - Frontiers in …, 2021 - frontiersin.org
The purpose of this study was to investigate the therapeutic effect of berberine (BBR) on
MNNG-induced chronic atrophic gastritis (CAG) and the possible mechanism of BBR …

Up-regulated Th17 cell function is associated with increased peptic ulcer disease in Helicobacter pylori-infection

N Bagheri, A Razavi, B Pourgheysari… - Infection, Genetics and …, 2018 - Elsevier
Abstract Background During Helicobacter pylori (H. pylori) infection CD4+ T cells in the
gastric lamina propria are hyporesponsive and polarized by Th1/Th17 cell responses …

Th17/Treg imbalance and increased interleukin-21 are associated with liver injury in patients with chronic severe hepatitis B

B Liu, W Gao, L Zhang, J Wang, M Chen… - International …, 2017 - Elsevier
Abstract Background Th17/Treg imbalance and the levels of related cytokines are essential
in the pathogenesis of autoimmune and infectious diseases. The aim of the current study …

Role of Th22 cells in Helicobacter pylori-related gastritis and peptic ulcer diseases

A Sanaii, H Shirzad, M Haghighian, G Rahimian… - Molecular biology …, 2019 - Springer
Helicobacter pylori (H. pylori) has been shown to be one of the leading causes of peptic
ulcer diseases (PUDs) and gastritis. T helper-22 (Th22) cells and its most important cytokine …

Proinflammatory Cytokine IL‐17 Shows a Significant Association with Helicobacter pylori Infection and Disease Severity

PS Arachchi, N Fernando… - Gastroenterology …, 2017 - Wiley Online Library
Background. The pro‐and anti‐inflammatory cytokines play an important role in the immune
response against H. pylori infection. The proinflammatory cytokines of Th17 cells have been …

Transforming growth factor-β: an important mediator in Helicobacter pylori-associated pathogenesis

N Li, C **e, NH Lu - Frontiers in cellular and infection microbiology, 2015 - frontiersin.org
Helicobacter pylori (H. pylori) is a Gram-negative, microaerophilic, helical bacillus that
specifically colonizes the gastric mucosa. The interaction of virulence factors, host genetic …

Helicobacter pylori infection downregulates duodenal CFTR and SLC26A6 expressions through TGFβ signaling pathway

G Wen, S Deng, W Song, H **, J Xu, X Liu, R **e… - BMC microbiology, 2018 - Springer
Abstract Background The pathogenesis of Helicobacter pylori (H. pylori) infection-induced
duodenal ulcer remains to be elucidated. Duodenal mucosal bicarbonate secretion is the …

Dynamic change of circulating innate and adaptive lymphocytes subtypes during a cascade of gastric lesions

W Fu, W Wang, J Zhang, Y Zhao, K Chen… - Journal of Leukocyte …, 2022 - academic.oup.com
According to the Correa model, the intestinal-type gastric cancer (GC) is preceded by
premalignant lesions, including chronic gastritis, intestinal metaplasia and dysplasia …