[HTML][HTML] Advances and challenges in the treatment of lung cancer

Y Li, B Yan, S He - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Lung cancer accounts for a relatively high proportion of malignant tumors. As the most
prevalent type of lung cancer, non-small cell lung cancer (NSCLC) is characterized by high …

[HTML][HTML] Multifaceted nanozymes for synergistic antitumor therapy: A review

Q Li, T Wu, X Fan, X Guo, W Jiang, K Fan - Materials & Design, 2022 - Elsevier
Although various cancer therapies have been developed in the last decade, much of their
anti-tumor effects are restricted by the tumor microenvironment complexity, such as the …

Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer

B Cao, M Liu, L Wang, K Zhu, M Cai, X Chen… - Nature …, 2022 - nature.com
The complex immunosuppressive tumour microenvironment (TME) and lack of tumour-
specific targets hinder the application of chimeric antigen receptor (CAR) T cells in the …

Nanotechnology-based approaches overcome lung cancer drug resistance through diagnosis and treatment

J Li, L Zhu, HF Kwok - Drug Resistance Updates, 2023 - Elsevier
Lung cancer continues to be a malignant tumor with high mortality. Two obstacles interfere
with curative therapy of lung cancer:(i) poor diagnosis at the early stages, as symptoms are …

Nanozyme-based remodeling of disease microenvironments for disease prevention and treatment: a review

Y Ju, X Liu, X Ye, M Dai, B Fang… - ACS Applied Nano …, 2023 - ACS Publications
Nanomaterials that can mimic the activity of various enzymes have been studied extensively
in the biomedical field in recent years. Nanozymes offer better stability and economic value …

Nanozyme‐based artificial organelles: an emerging direction for artificial organelles

S Zhang, R Zhang, X Yan, K Fan - Small, 2022 - Wiley Online Library
Artificial organelles are compartmentalized nanoreactors, in which enzymes or enzyme‐
mimic catalysts exhibit cascade catalytic activities to mimic the functions of natural …

Hurdles to breakthrough in CAR T cell therapy of solid tumors

F Marofi, H Achmad, D Bokov, WK Abdelbasset… - Stem Cell Research & …, 2022 - Springer
Autologous T cells genetically engineered to express chimeric antigen receptor (CAR) have
shown promising outcomes and emerged as a new curative option for hematological …

Rational nanomedicine design enhances clinically physical Treatment‐Inspired or combined immunotherapy

Q Liu, W Zhang, R Jiao, Z Lv, X Lin, Y **ao… - Advanced …, 2022 - Wiley Online Library
Independent of tumor type and non‐invasive or minimally‐invasive feature, current physical
treatments including ultrasound therapy, microwave ablation (MWA), and radiofrequency …

Modulating tumor physical microenvironment for fueling CAR-T cell therapy

Z Luo, X Yao, M Li, D Fang, Y Fei, Z Cheng, Y Xu… - Advanced drug delivery …, 2022 - Elsevier
Chimeric antigen receptor (CAR) T cell therapy has achieved unprecedented clinical
success against hematologic malignancies. However, the transition of CAR-T cell therapies …

Design and synthesis of cancer-cell-membrane-camouflaged hemoporfin-Cu9S8 nanoagents for homotypic tumor-targeted photothermal-sonodynamic therapy

Y Zhao, M Wen, N Yu, C Tao, Q Ren, P Qiu… - Journal of Colloid and …, 2023 - Elsevier
Multimodal therapies have aroused great interest in tumor therapy due to their highly
effective antitumor effect. However, immune clearance limits the practical application of …