[HTML][HTML] Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing
Wound management in diabetic patient is of an extreme clinical and social concern. The
delayed and impaired healing makes it more critical for research focus. The research on …
delayed and impaired healing makes it more critical for research focus. The research on …
Why venous leg ulcers have difficulty healing: overview on pathophysiology, clinical consequences, and treatment
JD Raffetto, D Ligi, R Maniscalco, RA Khalil… - Journal of clinical …, 2020 - mdpi.com
Venous leg ulcers (VLUs) are one of the most common ulcers of the lower extremity. VLU
affects many individuals worldwide, could pose a significant socioeconomic burden to the …
affects many individuals worldwide, could pose a significant socioeconomic burden to the …
A click chemistry-mediated all-peptide cell printing hydrogel platform for diabetic wound healing
High glucose-induced vascular endothelial injury is a major pathological factor involved in
non-healing diabetic wounds. To interrupt this pathological process, we design an all …
non-healing diabetic wounds. To interrupt this pathological process, we design an all …
Managing diabetic foot ulcers: pharmacotherapy for wound healing
D Dixon, M Edmonds - Drugs, 2021 - Springer
Historically, there has been a scarcity of evidence-based topical therapy to hasten the
healing of diabetic foot ulcers. But recently new evidence-based treatments have emerged …
healing of diabetic foot ulcers. But recently new evidence-based treatments have emerged …
Oxidative stress and lipid peroxidation: prospective associations between ferroptosis and delayed wound healing in diabetic ulcers
J Feng, J Wang, Y Wang, X Huang, T Shao… - Frontiers in cell and …, 2022 - frontiersin.org
Diabetic ulcers are one of the major complications of diabetes, and patients usually suffer
from amputation and death due to delayed ulcer wound healing. Persistent inflammation …
from amputation and death due to delayed ulcer wound healing. Persistent inflammation …
Development of a photosynthetic hydrogel as potential wound dressing for the local delivery of oxygen and bioactive molecules
The development of biomaterials to improve wound healing is a critical clinical challenge
and an active field of research. As it is well described that oxygen plays a critical role in …
and an active field of research. As it is well described that oxygen plays a critical role in …
Accelerated wound healing in a diabetic rat model using decellularized dermal matrix and human umbilical cord perivascular cells
There is an unmet clinical need for novel wound healing strategies to treat full thickness skin
defects, especially in diabetic patients. We hypothesized that a scaffold could perform dual …
defects, especially in diabetic patients. We hypothesized that a scaffold could perform dual …
Extracellular vesicle-based therapeutics for the regeneration of chronic wounds: current knowledge and future perspectives
P Lou, S Liu, X Xu, C Pan, Y Lu, J Liu - Acta biomaterialia, 2021 - Elsevier
Chronic wounds are still an intractable medical problem for both clinicians and researchers
and cause a substantial social and medical burden. Current clinical approaches can only …
and cause a substantial social and medical burden. Current clinical approaches can only …
Healing of chronic wounds: an update of recent developments and future possibilities
Chronic wounds are the result of disruptions in the body's usual process of healing. They are
not only a source of significant pain and discomfort but also, more importantly, an unguarded …
not only a source of significant pain and discomfort but also, more importantly, an unguarded …
Relevance of NLRP3 inflammasome‐related pathways in the pathology of diabetic wound healing and possible therapeutic targets
Wound healing is a major secondary complication in type 2 diabetes, which results in
significant disability and mortality, imposing a significant clinical and social burden …
significant disability and mortality, imposing a significant clinical and social burden …