[HTML][HTML] SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development

S Zhou, P Lv, M Li, Z Chen, H **n, S Reilly… - Biomedicine & …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating
global pandemic, which has seriously affected human health worldwide. The discovery of …

[HTML][HTML] Revisiting liquorice (Glycyrrhiza glabra L.) as anti-inflammatory, antivirals and immunomodulators: Potential pharmacological applications with mechanistic …

D Bisht, M Rashid, RKK Arya, D Kumar… - Phytomedicine Plus, 2022 - Elsevier
Abstract Background Glycyrrhiza glabra L.(G. glabra) commonly known as liquorice is one of
the highly exploited and utilized medicinal plant of the world. Since ancient times liquorice is …

A review of the antiviral activities of glycyrrhizic acid, glycyrrhetinic acid and glycyrrhetinic acid monoglucuronide

J Zuo, T Meng, Y Wang, W Tang - Pharmaceuticals, 2023 - mdpi.com
Licorice, a natural medicine derived from the roots and rhizomes of Glycyrrhiza species,
possesses a wide range of therapeutic applications, including antiviral properties …

Promising natural products against SARS‐CoV‐2: Structure, function, and clinical trials

Y Zhao, S Deng, Y Bai, J Guo, G Kai… - Phytotherapy …, 2022 - Wiley Online Library
The corona virus disease 2019 (COVID‐19) caused by severe acute respiratory syndrome
coronavirus type 2 (SARS‐COV‐2) poses a severe threat to human health and still spreads …

Colloidal aggregation confounds cell-based Covid-19 antiviral screens

IS Glenn, LN Hall, MM Khalid, M Ott… - Journal of Medicinal …, 2024 - ACS Publications
Colloidal aggregation is one of the largest contributors to false positives in early drug
discovery. Here, we consider aggregation's role in cell-based infectivity assays in Covid-19 …

Exploring the mechanism of action of licorice in the treatment of COVID-19 through bioinformatics analysis and molecular dynamics simulation

JF Cao, Y Gong, M Wu, X Yang, L **ong… - Frontiers in …, 2022 - frontiersin.org
Purpose: The rapid worldwide spread of Corona Virus Disease 2019 (COVID-19) has
become not only a global challenge, but also a lack of effective clinical treatments. Studies …

Plant‐derived compounds as potential leads for new drug development targeting COVID‐19

L Liu, M Kapralov, M Ashton - Phytotherapy Research, 2024 - Wiley Online Library
COVID‐19, which was first identified in 2019 in Wuhan, China, is a respiratory illness
caused by a virus called severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …

Advancing combination treatment with glycyrrhizin and boswellic acids for hospitalized patients with moderate COVID-19 infection: a randomized clinical trial

AA Gomaa, HS Mohamed, RB Abd-Ellatief… - …, 2022 - Springer
Recent evidence points to a potential therapeutic role for glycyrrhizin (GR) and boswellic
acids (BA) in the treatment of COVID-19 but conclusive evidence is lacking. Our aim is to …

Glycyrrhizin and boswellic acids, the golden nutraceuticals: multitargeting for treatment of mild–moderate COVID-19 and prevention of post-COVID cognitive …

AA Gomaa, YA Abdel-Wadood, MA Gomaa - Inflammopharmacology, 2022 - Springer
Breakthrough infections have been reported in fully vaccinated persons. Furthermore,
rebound symptoms have been reported following the new FDA granted emergency use to …

Triterpene derivatives as potential inhibitors of the RBD spike protein from SARS-CoV-2: an in silico approach

M Avelar, L Pedraza-González, A Sinicropi… - Molecules, 2023 - mdpi.com
The appearance of a new coronavirus, SARS-CoV-2, in 2019 kicked off an international
public health emergency. Although rapid progress in vaccination has reduced the number of …