Genetic variation associated with disease often appears in non-coding parts of the genome.
Understanding the mechanisms by which this phenomenon leads to disease is necessary to …

How a complex animal can arise from a fertilized egg is one of the oldest and most
fascinating questions of biology, the answer to which is encoded in the genome. Body shape …

The genome is partitioned into topologically associated domains and genomic
compartments with shared chromatin valence. This architecture is constrained by the DNA …

The simultaneous measurement of three-dimensional (3D) genome structure and gene
expression of individual cells is critical for understanding a genome's structure–function …

Olfactory receptors (ORs) are not exclusively expressed in the olfactory sensory neurons;
they are also observed outside of the olfactory system in all other human tissues tested to …

CTCF is a highly conserved zinc finger protein implicated in diverse regulatory functions,
including transcriptional activation/repression, insulation, imprinting, and X chromosome …

To accommodate genomes in the limited space of the cell nucleus and ensure the correct
execution of gene expression programs, genomes are packaged in complex fashion in the …

The biological olfactory system is the sensory system responsible for the detection of the
chemical composition of the environment. Several attempts to mimic biological olfactory …

In vivo, the human genome functions as a complex, folded, three-dimensional chromatin
polymer. Understanding how the human genome is spatially organized and folded inside …

Odor signals received by odorant receptors (ORs) expressed by olfactory sensory neurons
(OSNs) in the olfactory epithelium (OE) are represented as an odor map in the olfactory bulb …