Sex differences in heart failure
CSP Lam, C Arnott, AL Beale… - European heart …, 2019 - academic.oup.com
The overall lifetime risk of heart failure (HF) is similar between men and women, however,
there are marked sex differences in the landscape of this condition that are both important …
there are marked sex differences in the landscape of this condition that are both important …
Adverse effects of tyrosine kinase inhibitors in cancer therapy: pathophysiology, mechanisms and clinical management
S Shyam Sunder, UC Sharma… - Signal Transduction and …, 2023 - nature.com
Since their invention in the early 2000s, tyrosine kinase inhibitors (TKIs) have gained
prominence as the most effective pathway-directed anti-cancer agents. TKIs have shown …
prominence as the most effective pathway-directed anti-cancer agents. TKIs have shown …
[HTML][HTML] Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations
G Curigliano, D Lenihan, M Fradley, S Ganatra… - Annals of …, 2020 - Elsevier
Cancer and cardiovascular (CV) disease are the most prevalent diseases in the developed
world. Evidence increasingly shows that these conditions are interlinked through common …
world. Evidence increasingly shows that these conditions are interlinked through common …
Role of cardiovascular imaging in cancer patients receiving cardiotoxic therapies: a position statement on behalf of the H eart F ailure A ssociation (HFA), the E …
Cardiovascular (CV) imaging is an important tool in baseline risk assessment and detection
of CV disease in oncology patients receiving cardiotoxic cancer therapies. This position …
of CV disease in oncology patients receiving cardiotoxic cancer therapies. This position …
Medium and long-term risks of specific cardiovascular diseases in survivors of 20 adult cancers: a population-based cohort study using multiple linked UK electronic …
Background The past few decades have seen substantial improvements in cancer survival,
but concerns exist about long-term cardiovascular disease risk in survivors. Evidence is …
but concerns exist about long-term cardiovascular disease risk in survivors. Evidence is …
Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity
Environmental factors are the largest contributors to cardiovascular disease. Here we show
that cardiac organoids that incorporate an oxygen-diffusion gradient and that are stimulated …
that cardiac organoids that incorporate an oxygen-diffusion gradient and that are stimulated …
[HTML][HTML] Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
Mitochondrial DNA (mtDNA) is a potent agonist of the innate immune system; however, the
exact immunostimulatory features of mtDNA and the kinetics of detection by cytosolic nucleic …
exact immunostimulatory features of mtDNA and the kinetics of detection by cytosolic nucleic …
Incident cardiovascular disease among adults with cancer: a population-based cohort study
Background Patients with cancer and cancer survivors are at increased risk for incident
heart failure, but there are conflicting data on the long-term risk for other cardiovascular …
heart failure, but there are conflicting data on the long-term risk for other cardiovascular …
[HTML][HTML] Ten things to know about ten cardiovascular disease risk factors
Given rapid advancements in medical science, it is often challenging for the busy clinician to
remain up-to-date on the fundamental and multifaceted aspects of preventive cardiology and …
remain up-to-date on the fundamental and multifaceted aspects of preventive cardiology and …
Classification, prevalence, and outcomes of anticancer therapy-induced cardiotoxicity: the CARDIOTOX registry
J Lopez-Sendon, C Alvarez-Ortega… - European heart …, 2020 - academic.oup.com
Abstract Aim Cardiotoxicity (CTox) is a major side effect of cancer therapies, but uniform
diagnostic criteria to guide clinical and research practices are lacking. Methods and results …
diagnostic criteria to guide clinical and research practices are lacking. Methods and results …