Aging remains a primary risk factor for a host of diseases, including leading causes of death.
Aging and associated diseases are inherently multifactorial, with numerous contributing …

Introduction Arthrofibrosis remains a common cause of patient dissatisfaction and
reoperation after total knee arthroplasty (TKA). Losartan is an angiotensin receptor blocker …

Background and hypothesis After massive tears, rotator cuff muscle often undergoes
atrophy, fibrosis, and fatty degeneration. These changes can lead to high surgical failure …

Sarcopenia is the age-related loss of skeletal muscle mass and function. Skeletal muscle
comprises diverse progenitor cells, including mesenchymal progenitor cells (MPCs), which …

Endothelial dysfunction, with increased endothelin-1 (ET-1) synthesis, and sarcopenia,
characterized by the loss of muscular mass and strength, are two aging–related conditions …

Study Design Intraexaminer and interexaminer, within-and between-day reliability study.
Objectives To compare the intraexaminer and interexaminer procedural reliability of …

Bothrops atrox snakes are the leading cause of snake bites in Northern Brazil. The venom of
this snake is not included in the antigen pool used to obtain the Bothrops antivenom. There …

Background The cellular mechanisms underlying excess scar tissue formation in
arthrofibrosis following total knee arthroplasty (TKA) are well-described. Angiotensin …

Fibrosis is a broad pathology of excessive scarring with substantial medical implications.
The fibrotic scar is produced by myofibroblasts that interact with macrophages. Fibrosis is a …

Skeletal muscle maintenance and repair is dependent on the resident adult muscle stem cell
(MuSC). During injury, and in diseased muscle, stem cells are engaged to replace or repair …