The neurobiology of irritable bowel syndrome
Irritable bowel syndrome (IBS) is the most prevalent disorder of brain-gut interactions that
affects between 5 and 10% of the general population worldwide. The current symptom …
affects between 5 and 10% of the general population worldwide. The current symptom …
Neuroimmune interactions in the intestine
A Wallrapp, IM Chiu - Annual Review of Immunology, 2024 - annualreviews.org
Recent advances have contributed to a mechanistic understanding of neuroimmune
interactions in the intestine and revealed an essential role of this cross talk for gut …
interactions in the intestine and revealed an essential role of this cross talk for gut …
Gut enterochromaffin cells drive visceral pain and anxiety
Gastrointestinal (GI) discomfort is a hallmark of most gut disorders and represents an
important component of chronic visceral pain. For the growing population afflicted by irritable …
important component of chronic visceral pain. For the growing population afflicted by irritable …
Pain in endometriosis
Endometriosis is a chronic and debilitating condition affecting∼ 10% of women.
Endometriosis is characterized by infertility and chronic pelvic pain, yet treatment options …
Endometriosis is characterized by infertility and chronic pelvic pain, yet treatment options …
[HTML][HTML] Pain regulation by gut microbiota: molecular mechanisms and therapeutic potential
The relationship between gut microbiota and neurological diseases, including chronic pain,
has received increasing attention. The gut microbiome is a crucial modulator of visceral …
has received increasing attention. The gut microbiome is a crucial modulator of visceral …
Peripheral nerves directly mediate the transneuronal translocation of silver nanomaterials from the gut to central nervous system
The blood circulation is considered the only way for the orally administered nanoparticles to
enter the central nervous systems (CNS), whereas non-blood route-mediated nanoparticle …
enter the central nervous systems (CNS), whereas non-blood route-mediated nanoparticle …
Mechanisms of action of fascial plane blocks: a narrative review
KJ Chin, P Lirk, MW Hollmann… - Regional Anesthesia & …, 2021 - rapm.bmj.com
Background Fascial plane blocks (FPBs) target the space between two fasciae, rather than
discrete peripheral nerves. Despite their popularity, their mechanisms of action remain …
discrete peripheral nerves. Despite their popularity, their mechanisms of action remain …
Neuroimmune interactions in peripheral organs
Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …
recent studies show that this crosstalk occurs more frequently than was previously …
[HTML][HTML] Gut-innervating nociceptor neurons regulate Peyer's patch microfold cells and SFB levels to mediate Salmonella host defense
Gut-innervating nociceptor sensory neurons respond to noxious stimuli by initiating
protective responses including pain and inflammation; however, their role in enteric …
protective responses including pain and inflammation; however, their role in enteric …
The enteric nervous system in gastrointestinal disease etiology
AM Holland, AC Bon-Frauches, D Keszthelyi… - Cellular and Molecular …, 2021 - Springer
A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …