Magnetic drug delivery: where the field is going

PM Price, WE Mahmoud, AA Al-Ghamdi… - Frontiers in …, 2018 - frontiersin.org
Targeted delivery of anticancer drugs is considered to be one of the pillars of cancer
treatment as it could allow for a better treatment efficiency and less adverse effects. A …

Nanomaterials and their impact on the immune system

AA Aljabali, MA Obeid, RM Bashatwah… - International journal of …, 2023 - mdpi.com
Nanomaterials have been the focus of intensive development and research in the medical
and industrial sectors over the past several decades. Some studies have found that these …

Intra/extracellular lactic acid exhaustion for synergistic metabolic therapy and immunotherapy of tumors

F Gao, Y Tang, WL Liu, MZ Zou, C Huang… - Advanced …, 2019 - Wiley Online Library
Regulating the tumor microenvironment (TME) has been a promising strategy to improve
antitumor therapy. Here, a red blood cell membrane (mRBC)‐camouflaged hollow MnO2 …

Engineering the drug carrier biointerface to overcome biological barriers to drug delivery

JA Finbloom, F Sousa, MM Stevens… - Advanced drug delivery …, 2020 - Elsevier
Micro and nanoscale drug carriers must navigate through a plethora of dynamic biological
systems prior to reaching their tissue or disease targets. The biological obstacles to drug …

Platelet membrane biomimetic bufalin-loaded hollow MnO2 nanoparticles for MRI-guided chemo-chemodynamic combined therapy of cancer

H Wang, DH Bremner, K Wu, X Gong, Q Fan… - Chemical Engineering …, 2020 - Elsevier
In this study, platelet membrane (PLTM) biomimetic hollow MnO 2 nanoparticles were
prepared and these were investigated for delivery of bufalin. Additionally, these …

Nanosponges of circulating tumor-derived exosomes for breast cancer metastasis inhibition

H Ye, K Wang, Q Lu, J Zhao, M Wang, Q Kan, H Zhang… - Biomaterials, 2020 - Elsevier
Breast cancer contributes to high mortality rates as a result of metastasis. Tumor-derived
exosomes facilitate the development of the premetastatic environment, interacting and …

Zwitterionic polymers: addressing the barriers for drug delivery

M Li, W Zhang, J Li, Y Qi, C Peng, N Wang, H Fan… - Chinese Chemical …, 2023 - Elsevier
Nanocarriers play an important role in drug delivery for disease treatment. However,
nanocarriers face a series of physiological barriers after administration such as blood …

Hide and seek: Nanomaterial interactions with the immune system

B Fadeel - Frontiers in immunology, 2019 - frontiersin.org
Engineered nanomaterials hold promise for a wide range of applications in medicine.
However, safe use of nanomaterials requires that interactions with biological systems, not …

Artificial chimeric exosomes for anti-phagocytosis and targeted cancer therapy

KL Zhang, YJ Wang, J Sun, J Zhou, C **ng… - Chemical …, 2019 - pubs.rsc.org
Development of exosome-based delivery systems is still facing some formidable challenges,
including the lack of standardized isolation and purification methods, non-large-scale …

New Insight about Biocompatibility and Biodegradability of Iron Oxide Magnetic Nanoparticles: Stereological and In Vivo MRI Monitor

H Nosrati, M Salehiabar, M Fridoni, MA Abdollahifar… - Scientific reports, 2019 - nature.com
Iron oxide magnetic nanoparticles (IONPs) have attracted enormous attention because of
their extensive medicinal and industrial applicability. PEGylated L-arginine modified iron …