Multienzyme‐like nanozymes: regulation, rational design, and application

J Sheng, Y Wu, H Ding, K Feng, Y Shen… - Advanced …, 2024 - Wiley Online Library
Nanomaterials with more than one enzyme‐like activity are termed multienzymic
nanozymes, and they have received increasing attention in recent years and hold huge …

Structure, properties and applications of two‐dimensional hexagonal boron nitride

S Roy, X Zhang, AB Puthirath… - Advanced …, 2021 - Wiley Online Library
Hexagonal boron nitride (h‐BN) has emerged as a strong candidate for two‐dimensional
(2D) material owing to its exciting optoelectrical properties combined with mechanical …

Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis

F Cao, L **, Y Gao, Y Ding, H Wen, Z Qian… - Nature …, 2023 - nature.com
Inflammatory bowel disease can be caused by the dysfunction of the intestinal mucosal
barrier and dysregulation of gut microbiota. Traditional treatments use drugs to manage …

An immunomodulatory hydrogel by hyperthermia‐assisted self‐cascade glucose depletion and ROS scavenging for diabetic foot ulcer wound therapeutics

X Qi, E Cai, Y **ang, C Zhang, XX Ge… - Advanced …, 2023 - Wiley Online Library
Current therapeutic protocols for diabetic foot ulcers (DFUs), a severe and rapidly growing
chronic complication in diabetic patients, remain nonspecific. Hyperglycemia‐caused …

Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery

J Zhou, M Li, Q Chen, X Li, L Chen, Z Dong… - Nature …, 2022 - nature.com
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore,
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …

Catalase‐like nanozymes: Classification, catalytic mechanisms, and their applications

D Xu, L Wu, H Yao, L Zhao - Small, 2022 - Wiley Online Library
The field of nanozymes has developed rapidly over the past decade. Among various
oxidoreductases mimics, catalase (CAT)‐like nanozyme, acting as an essential part of the …

Nanozymes-recent development and biomedical applications

X Ren, D Chen, Y Wang, H Li, Y Zhang, H Chen… - Journal of …, 2022 - Springer
Nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with
the catalytic reactions of natural enzymes. In the field of biomedicine, nanozymes are …

Bioinspired copper single‐atom nanozyme as a superoxide dismutase‐like antioxidant for sepsis treatment

J Yang, R Zhang, H Zhao, H Qi, J Li, JF Li, X Zhou… - …, 2022 - Wiley Online Library
Sepsis is a systemic inflammatory response syndrome with high morbidity and mortality
mediated by infection‐caused oxidative stress. Early antioxidant intervention by removing …

Designing nanozymes for in vivo applications

R Zhang, B Jiang, K Fan, L Gao, X Yan - Nature Reviews …, 2024 - nature.com
Biocatalytic drugs, including natural and artificial enzymes that can accelerate biochemical
reactions, are promising tools to address redox imbalances, metabolic disorders and …

Recent advances in nanozymes: from matters to bioapplications

Y Ai, ZN Hu, X Liang, H Sun, H **n… - Advanced Functional …, 2022 - Wiley Online Library
The manufacture of bionic materials to simulate the natural counterparts has attracted
extensive attention. As one of the subcategories of biomimetic materials, the development of …