The human cerebral cortex undergoes dramatic and critical development during early
postnatal stages. Benefiting from advances in neuroimaging, many infant brain magnetic …

The formation of myelin, the fatty sheath that insulates nerve fibers, is critical for healthy
brain function. A fundamental open question is what impact being born has on myelin …

Myelination is an important process in the central nervous system (CNS). Oligodendrocytes
(OLs) extend multiple layers to densely sheath on axons, composing the myelin to achieve …

Gene replacement therapy is a rational therapeutic strategy and clinical intervention for
neurodegenerative disorders like Canavan disease, a leukodystrophy caused by biallelic …

Using machine learning techniques to predict brain age from multimodal data has become a
crucial biomarker for assessing brain development. Among various types of brain imaging …

Background Creatine supplementation during pregnancy is a promising prophylactic
treatment for perinatal hypoxic brain injury. Previously, in near-term sheep we have shown …

The thalamus plays a crucial role in the development of the neocortex, with the pulvinar
being particularly important for visual development due to its involvement in various …

Prenatal life and childhood represent periods that are vulnerable to environmental
exposures. Both cold and heat may have negative impacts on children's mental health and …