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Macrophages in cardiovascular diseases: molecular mechanisms and therapeutic targets
R Chen, H Zhang, B Tang, Y Luo, Y Yang… - Signal transduction and …, 2024 - nature.com
The immune response holds a pivotal role in cardiovascular disease development. As
multifunctional cells of the innate immune system, macrophages play an essential role in …
multifunctional cells of the innate immune system, macrophages play an essential role in …
Biomarkers of oxidative stress in metabolic syndrome and associated diseases
R Vona, L Gambardella, C Cittadini… - Oxidative medicine …, 2019 - Wiley Online Library
Metabolic syndrome (MS) represents worldwide public health issue characterized by a set of
cardiovascular risk factors including obesity, diabetes, dyslipidemia, hypertension, and …
cardiovascular risk factors including obesity, diabetes, dyslipidemia, hypertension, and …
Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy
Even in the absence of coronary artery disease and hypertension, diabetes mellitus (DM)
may increase the risk for heart failure development. This risk evolves from functional and …
may increase the risk for heart failure development. This risk evolves from functional and …
A review of the molecular mechanisms underlying the development and progression of cardiac remodeling
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter
the existing structure of the heart, leading to cardiac dysfunction. Among the complex …
the existing structure of the heart, leading to cardiac dysfunction. Among the complex …
Diabetes-associated cardiac fibrosis: cellular effectors, molecular mechanisms and therapeutic opportunities
Both type 1 and type 2 diabetes are associated with cardiac fibrosis that may reduce
myocardial compliance, contribute to the pathogenesis of heart failure, and trigger …
myocardial compliance, contribute to the pathogenesis of heart failure, and trigger …
Diabetic cardiovascular disease induced by oxidative stress
Y Kayama, U Raaz, A Jagger, M Adam… - International journal of …, 2015 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among
patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications …
patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications …
Redox signaling in diabetic wound healing regulates extracellular matrix deposition
Significance: Impaired wound healing is a major complication of diabetes, and can lead to
development of chronic foot ulcers in a significant number of patients. Despite the danger …
development of chronic foot ulcers in a significant number of patients. Despite the danger …
[HTML][HTML] Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy
Diabetes is a recognized risk factor for cardiovascular diseases and heart failure. Diabetic
cardiovascular dysfunction also underscores the development of diabetic retinopathy …
cardiovascular dysfunction also underscores the development of diabetic retinopathy …
Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment
Diabetes mellitus is an important and prevalent risk factor for congestive heart failure.
Diabetic cardiomyopathy has been defined as ventricular dysfunction that occurs in diabetic …
Diabetic cardiomyopathy has been defined as ventricular dysfunction that occurs in diabetic …
Mitochondrial aldehyde dehydrogenase (ALDH2) rescues cardiac contractile dysfunction in an APP/PS1 murine model of Alzheimer's disease via inhibition of ACSL4 …
Alzheimer's disease (AD) is associated with high incidence of cardiovascular events but the
mechanism remains elusive. Our previous study reveals a tight correlation between cardiac …
mechanism remains elusive. Our previous study reveals a tight correlation between cardiac …