Role of fluid dynamics in infectious disease transmission: insights from COVID-19 and other pathogens

S Koley - Trends in Sciences, 2024‏ - tis.wu.ac.th
The spread of infectious diseases such as COVID-19 depends on complex fluid dynamics
interactions between pathogens and fluid phases, including individual droplets and …

[HTML][HTML] Polystyrene microplastics alter the trophic transfer and biotoxicity of fluoxetine in an aquatic food chain

Z Yan, H Zhao, P Zhu, Y Wang, J Hou, G Lu… - Journal of Hazardous …, 2024‏ - Elsevier
Microplastics (MPs) and fluoxetine are ubiquitous emerging pollutants in aquatic
environments that may interact with each other due to the carrier effects of MPs, posing …

The dose disrupts the pathway: application of Paracelsus principle to mechanistic toxicology

A Suvorov - Toxicological Sciences, 2024‏ - academic.oup.com
Arguably the most famous principle of toxicology is “The dose makes the poison” formulated
by Paracelsus in the 16th century. Application of the Paracelsus's principle to mechanistic …

Organoid intelligence for developmental neurotoxicity testing

DM Alam El Din, J Shin, A Lysinger, MJ Roos… - Frontiers in Cellular …, 2024‏ - frontiersin.org
The increasing prevalence of neurodevelopmental disorders has highlighted the need for
improved testing methods to determine developmental neurotoxicity (DNT) hazard for …

PLLA Porous Scaffold as a 3D Breast Cancer Model to Investigate Drug Resistance

C Carbone, S Rigogliuso, VMB Brucato… - … Research Part A, 2025‏ - Wiley Online Library
Multidrug resistance remains one of the major challenges in breast cancer research, often
leading to treatment failure. To better understand this mechanism, sophisticated three …

Inferring gene regulatory networks of ALS from blood transcriptome profiles

XG Pappalardo, G Jansen, M Amaradio, J Costanza… - Heliyon, 2024‏ - cell.com
One of the most robust approaches to the prediction of causal driver genes of complex
diseases is to apply reverse engineering methods to infer a gene regulatory network (GRN) …

Animal models in neuroscience with alternative approaches: Evolutionary, biomedical, and ethical perspectives

S Neziri, AE Köseoğlu… - Animal Models and …, 2024‏ - Wiley Online Library
Animal models have been a crucial tool in neuroscience research for decades, providing
insights into the biomedical and evolutionary mechanisms of the nervous system, disease …

[PDF][PDF] The zebrafish (Danio rerio): a dynamic model organism for Scientific Research

RK Alla, A Konakanchi, R Nallakunta, SR AV… - Uttar Pradesh J …, 2024‏ - researchgate.net
Zebrafish has become a fundamental model organism in biomedical research due to their
genetic similarity to humans, rapid development, and transparent embryos. In …

[HTML][HTML] Advancing osseointegration research: A dynamic three-dimensional (3D) in vitro culture model for dental implants

K Komatsu, D Chao, T Matsuura, D Kido… - Journal of Dental …, 2025‏ - Elsevier
Background/purpose In-vitro studies are essential for understanding cellular responses, but
traditional culture systems often neglect the three-dimensional (3D) structure of real …

Daniellia oliveri as a type 2 diabetes remedy: evidence from in-silico evaluation

SB Adeyemi, AA Saliu, BP Joshi… - Egyptian Journal of …, 2024‏ - Taylor & Francis
The prevalence of diabetes mellitus is increasing, and well-known conventional medications
are associated with harmful effects. Therefore, this study aimed to identify the compounds …