Transcription is regulated by acetylation/deacetylation reactions of histone and nonhistone
proteins mediated by enzymes called KATs and HDACs, respectively. As a major …

The silent information regulator (SIR) genes (sirtuins) comprise a highly conserved family of
proteins, with one or more sirtuins present in virtually all species from bacteria to mammals …

Long non‐coding RNAs (lncRNAs) have received particular attention in the last decade due
to its engaging in carcinogenesis and tumorigenesis. Metastasis‐associated lung …

Aims Oxidative stress plays a crucial role in the pathogenesis of multiple sclerosis (MS).
Melatonin has a central role in the modulation of oxidative stress pathways. We aimed to …

Lung inflammation and alveolar epithelial cell death are critical events in the development
and progression of acute lung injury (ALI). Although angiopoietin‐like protein 4 (ANGPTL4) …

Objectives SIRT1 is an antioxidative factor, but its mechanism in methamphetamine (MA)‐
induced lung injury remains unclear. The purpose of this study is to determine whether MA …

Polycystic ovarian syndrome (PCOS) is the most common multifactor heterogeneous
endocrine and metabolic disease in women of childbearing age. PCOS is a group of clinical …

The maintenance of homeostasis is essential for mitigating stress and delaying
degenerative diseases such as Alzheimer's disease (AD). AD is generally defined as the …

Background The present study analyzes the influence of resistance training (RT) and high-
intensity interval training (HIIT) on metabolic indices and serum levels of Sirtuin1 (SIRT1) in …

Results: Functional and hemodynamic variables did not differ between groups of athletes,
whereas there were dramatic changes in serum markers for oxidative stress. Lipid …