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[HTML][HTML] Obesity management in the primary prevention of hepatocellular carcinoma
Simple Summary Hepatocellular carcinoma (HCC) is an increasingly prevalent and deadly
disease driven in part by the rising obesity epidemic. Obesity causes HCC by initiating and …
disease driven in part by the rising obesity epidemic. Obesity causes HCC by initiating and …
Revisiting the concepts of de novo lipogenesis to understand the conversion of carbohydrates into fats: stop overvaluing and extrapolating the renowned phrase" fat …
Carbohydrates can be converted into fatty acids via de novo lipogenesis (DNL). Although
DNL is considered inefficient, these endogenous fatty acids contribute substantially to the …
DNL is considered inefficient, these endogenous fatty acids contribute substantially to the …
[HTML][HTML] Effect of an Asian-adapted Mediterranean diet and pentadecanoic acid on fatty liver disease: The TANGO randomized controlled trial
Background Weight loss is the most effective treatment for nonalcoholic fatty liver disease
(NAFLD). There is evidence that the Mediterranean diets rich in unsaturated fatty acids and …
(NAFLD). There is evidence that the Mediterranean diets rich in unsaturated fatty acids and …
[HTML][HTML] Reduction of De Novo lipogenesis mediates beneficial effects of isoenergetic diets on fatty liver: mechanistic insights from the MEDEA randomized clinical trial
G Costabile, G Della Pepa, D Salamone, D Luongo… - Nutrients, 2022 - mdpi.com
Background: Non-alcoholic liver steatosis (NAS) results from an imbalance between hepatic
lipid storage, disposal, and partitioning. A multifactorial diet high in fiber, monounsaturated …
lipid storage, disposal, and partitioning. A multifactorial diet high in fiber, monounsaturated …
[HTML][HTML] Lipid metabolism in MASLD and MASH: From mechanism to the clinic
Abstract Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD) is recognized
as a metabolic disease characterized by excess intrahepatic lipid accumulation due to lipid …
as a metabolic disease characterized by excess intrahepatic lipid accumulation due to lipid …
Carbohydrates deteriorate fatty liver by activating the inflammatory response
Y Gao, R Hua, K Hu, Z Wang - Nutrition research reviews, 2022 - cambridge.org
Non-alcoholic fatty liver disease (NAFLD) was defined in 1980 and has the same
histological characteristics as alcoholic liver disease except for alcohol consumption. After …
histological characteristics as alcoholic liver disease except for alcohol consumption. After …
An isoenergetic multifactorial diet reduces pancreatic fat and increases postprandial insulin response in patients with type 2 diabetes: a randomized controlled trial
OBJECTIVE To compare the effect of an isocaloric multifactorial diet with a diet rich in
monounsaturated fatty acids (MUFA) and similar macronutrient composition on pancreatic …
monounsaturated fatty acids (MUFA) and similar macronutrient composition on pancreatic …
Intrapancreatic fat deposition and nutritional treatment: the role of various dietary approaches
G Della Pepa, D Salamone, R Testa… - Nutrition …, 2024 - academic.oup.com
Ectopic fat accumulation in various organs and tissues, such as the liver, muscle, kidney,
heart, and pancreas, is related to impaired capacity of adipose tissue to accumulate …
heart, and pancreas, is related to impaired capacity of adipose tissue to accumulate …
Circulating short-chain fatty acids in type 2 diabetic patients and overweight/obese individuals
D Salamone, G Costabile, A Corrado, G Della Pepa… - Acta Diabetologica, 2022 - Springer
Aim aim of the study was to evaluate serum short chain fatty acids (SCFA) concentrations in
patients with Type 2 diabetes (T2D) and overweight/obese individuals. Methods In forty …
patients with Type 2 diabetes (T2D) and overweight/obese individuals. Methods In forty …
[HTML][HTML] Diet quality, cardiometabolic risk and diabetes
G Della Pepa - Nutrients, 2023 - mdpi.com
The alarming rise in obesity worldwide is a dramatic public health concern [1], and changes
in lifestyle factors, such as low physical activity and the progressive diffusion of the high …
in lifestyle factors, such as low physical activity and the progressive diffusion of the high …