Frailty: a global health challenge in need of local action

SD Dlima, A Hall, AQ Aminu, A Akpan, C Todd… - BMJ Global …, 2024 - gh.bmj.com
Frailty is a complex, age-related clinical condition that involves multiple contributing factors
and raises the risk of adverse outcomes in older people. Given global population ageing …

Frailty and biological age. Which best describes our aging and longevity?

J Félix, IM de Toda, E Díaz-Del Cerro… - Molecular Aspects of …, 2024 - Elsevier
Abstract Frailty and Biological Age are two closely related concepts; however, frailty is a
multisystem geriatric syndrome that applies to elderly subjects, whereas biological age is a …

Changes in frailty and incident cardiovascular disease in three prospective cohorts

D He, Z Wang, J Li, K Yu, Y He, X He, Y Liu… - European heart …, 2024 - academic.oup.com
Abstract Background and Aims Previous studies found that frailty was an important risk factor
for cardiovascular disease (CVD). However, previous studies only focused on baseline …

[HTML][HTML] Frailty and loneliness in older adults: A narrative review

AC Gheorghe, E Bălășescu, I Hulea, G Turcu… - Geriatrics, 2024 - mdpi.com
(1) Background: In a society with an advancing aging rate, medical systems are coming
under pressure due to an increasing flow of older patients with multiple somatic diseases …

Geroscience-centric perspective for geriatric psychiatry: integrating aging biology with geriatric mental health research

BS Diniz, J Seitz-Holland, R Sehgal, J Kasamoto… - The American Journal of …, 2024 - Elsevier
The geroscience hypothesis asserts that physiological aging is caused by a small number of
biological pathways. Despite the explosion of geroscience research over the past couple of …

Risk and protective factors for frailty in pre-frail and frail older adults

J Corral-Pérez, L Ávila-Cabeza-de-Vaca… - International journal of …, 2023 - mdpi.com
This study aims to evaluate the differences in body composition, physical function, and
physical activity between pre-frail/frail older adults and to detect risk and protective factors …

Living longer but frailer? Temporal trends in life expectancy and frailty in older Swedish adults

C Tazzeo, D Rizzuto… - The Journals of …, 2024 - academic.oup.com
Background This study aims to examine temporal trends in frailty state transitions, and years
spent frail, in older Swedish adults. Methods We followed the Swedish National Study on …

Relationship between physical activity and perceptions of ageing from the perspective of healthy ageing among older people with frailty with chronic disease: a cross …

YR Wang, HF Lee, PL Hsieh, CH Chang, CM Chen - BMC nursing, 2023 - Springer
Abstract Background In Taiwan, the 2019 Elderly Frailty Assessment found that 11.2% of
older people have frailty problems. Some researchers have found that older persons' …

U-shaped association of systemic immune-inflammation index levels with cancer-related and all-cause mortality in middle-aged and older individuals with frailty

Z Zheng, H Luo, Q Xue - Archives of Gerontology and Geriatrics, 2024 - Elsevier
Purpose Frailty is a state of heightened vulnerability to stress, whether from within the body
or external factors. We aim to assess the prognostic value of the Systemic Immune …

[HTML][HTML] Association of Frailty Index at 66 Years of Age with Health Care Costs and Utilization Over 10 Years in Korea: Retrospective Cohort Study

J Jang, A Kim, M Choi, EP McCarthy… - JMIR Public Health …, 2025 - publichealth.jmir.org
Background: The long-term economic impact of frailty measured at the beginning of
elderhood is unknown. Objective: The objective of our study was to examine the association …