A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

Microfluidic‐based approaches in targeted cell/particle separation based on physical properties: fundamentals and applications

R Nasiri, A Shamloo, S Ahadian, L Amirifar, J Akbari… - Small, 2020 - Wiley Online Library
Cell separation is a key step in many biomedical research areas including biotechnology,
cancer research, regenerative medicine, and drug discovery. While conventional cell sorting …

Lab on a chip for continuous-flow magnetic cell separation

M Hejazian, W Li, NT Nguyen - Lab on a Chip, 2015 - pubs.rsc.org
Separation of cells is a key application area of lab-on-a-chip (LOC) devices. Among the
various methods, magnetic separation of cells utilizing microfluidic devices offers the merits …

Fundamentals and application of magnetic particles in cell isolation and enrichment: a review

BD Plouffe, SK Murthy, LH Lewis - Reports on Progress in …, 2014 - iopscience.iop.org
Magnetic sorting using magnetic beads has become a routine methodology for the
separation of key cell populations from biological suspensions. Due to the inherent ability of …

Multiphysics microfluidics for cell manipulation and separation: a review

H Cha, H Fallahi, Y Dai, D Yuan, H An, NT Nguyen… - Lab on a Chip, 2022 - pubs.rsc.org
Multiphysics microfluidics, which combines multiple functional physical processes in a
microfluidics platform, is an emerging research area that has attracted increasing interest for …

Basic principles and recent advances in magnetic cell separation

M Frenea-Robin, J Marchalot - Magnetochemistry, 2022 - mdpi.com
Magnetic cell separation has become a key methodology for the isolation of target cell
populations from biological suspensions, covering a wide spectrum of applications from …

Rare cell isolation and analysis in microfluidics

Y Chen, P Li, PH Huang, Y **e, JD Mai, L Wang… - Lab on a Chip, 2014 - pubs.rsc.org
Rare cells are low-abundance cells in a much larger population of background cells.
Conventional benchtop techniques have limited capabilities to isolate and analyze rare cells …

Recent advances and current challenges in magnetophoresis based micro magnetofluidics

A Munaz, MJA Shiddiky, NT Nguyen - Biomicrofluidics, 2018 - pubs.aip.org
The combination of magnetism and microscale fluid flow has opened up a new era for
handling and manipulation of samples in microfluidics. In particular, magnetophoresis, the …

Microfluidic sample preparation for single cell analysis

S Hosic, SK Murthy, AN Koppes - Analytical chemistry, 2016 - ACS Publications
Single cell analysis is the measurement of transcription, translation, regulatory, and
signaling events within individual cells at the molecular level. The goal is to analyze and …

Microfluidic blood cell sorting: now and beyond

ZTF Yu, KM Aw Yong, J Fu - Small, 2014 - Wiley Online Library
Blood plays an important role in homeostatic regulation with each of its cellular components
having important therapeutic and diagnostic uses. Therefore, separation and sorting of …