The yeast deletion collection: a decade of functional genomics
The yeast deletion collections comprise> 21,000 mutant strains that carry precise start-to-
stop deletions of∼ 6000 open reading frames. This collection includes heterozygous and …
stop deletions of∼ 6000 open reading frames. This collection includes heterozygous and …
Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries
KK Hong, J Nielsen - Cellular and Molecular Life Sciences, 2012 - Springer
Metabolic engineering is the enabling science of development of efficient cell factories for
the production of fuels, chemicals, pharmaceuticals, and food ingredients through microbial …
the production of fuels, chemicals, pharmaceuticals, and food ingredients through microbial …
Rewiring carbon metabolism in yeast for high level production of aromatic chemicals
The production of bioactive plant compounds using microbial hosts is considered a safe,
cost-competitive and scalable approach to their production. However, microbial production …
cost-competitive and scalable approach to their production. However, microbial production …
Systems biology of metabolism
J Nielsen - Annual review of biochemistry, 2017 - annualreviews.org
Metabolism is highly complex and involves thousands of different connected reactions; it is
therefore necessary to use mathematical models for holistic studies. The use of …
therefore necessary to use mathematical models for holistic studies. The use of …
Engineering plant secondary metabolism in microbial systems
Engineering Plant Secondary Metabolism in Microbial Systems | Plant Physiology | Oxford
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A comprehensive comparison of RNA-Seq-based transcriptome analysis from reads to differential gene expression and cross-comparison with microarrays: a case …
RNA-seq, has recently become an attractive method of choice in the studies of
transcriptomes, promising several advantages compared with microarrays. In this study, we …
transcriptomes, promising several advantages compared with microarrays. In this study, we …
Real-time metabolome profiling of the metabolic switch between starvation and growth
Metabolic systems are often the first networks to respond to environmental changes, and the
ability to monitor metabolite dynamics is key for understanding these cellular responses …
ability to monitor metabolite dynamics is key for understanding these cellular responses …
Deconstructing Cell-Free Extract Preparation for in Vitro Activation of Transcriptional Genetic Circuitry
Recent advances in cell-free gene expression (CFE) systems have enabled their use for a
host of synthetic biology applications, particularly for rapid prototy** of genetic circuits and …
host of synthetic biology applications, particularly for rapid prototy** of genetic circuits and …
[HTML][HTML] CRISPR–Cas system enables fast and simple genome editing of industrial Saccharomyces cerevisiae strains
There is a demand to develop 3rd generation biorefineries that integrate energy production
with the production of higher value chemicals from renewable feedstocks. Here, robust and …
with the production of higher value chemicals from renewable feedstocks. Here, robust and …
De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial …
Abstract Saccharomyces cerevisiae CEN. PK 113-7D is widely used for metabolic
engineering and systems biology research in industry and academia. We sequenced …
engineering and systems biology research in industry and academia. We sequenced …