The molecular basis for metameric pattern in the Drosophila embryo

M Akam - Development, 1987 - journals.biologists.com
The metameric organization of the Drosophila embryo is generated in the first 5 h after
fertilization. An initially rather simple pattern provides the foundation for subsequent …

[PDF][PDF] Homeotic genes and the homeobox

WJ Gehring, Y Hiromi - Annual review of genetics, 1986 - Citeseer
The term" homeosis"(originally spelled" homoeosis") was proposed by Bateson (8) to
describe the transformation of one structure of the body into the homologous structure of …

Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

K Basler, G Struhl - Nature, 1994 - nature.com
Drosophila limbs are subdivided into anterior and posterior compartments which derive from
adjacent cell populations founded early in development. Evidence is now provided that …

Determination of Anteroposterior Polarity in Drosophila

C Nüsslein-Volhard, HG Frohnhöfer, R Lehmann - Science, 1987 - science.org
The principles of pattern formation in embryogenesis can be studied in Drosophila by means
of a powerful combination of genetic and transplantation experiments. The segmented …

Mitotic domains reveal early commitment of cells in Drosophila embryos

VE Foe - Development, 1989 - journals.biologists.com
In embryos of Drosophila melanogaster all the nuclei in the syncytial egg divide with global
synchrony during the first 13 mitotic cycles. But with cellularization in the 14th cycle, global …

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

JJ Lee, DP von Kessler, S Parks, PA Beachy - Cell, 1992 - cell.com
The segment polarity genes engrailed and wingless are expressed in neighboring stripes of
cells on opposite sides of the Drosophila parasegment boundary. Each gene is mutually …

Morphogens, compartments, and pattern: lessons from Drosophila?

PA Lawrence, G Struhl - Cell, 1996 - cell.com
Peter A. Lawrence* and Gary Struhl† Epigenesis, at least in Drosophila, depends on three
steps which interlock and overlap; we simplify and refer* Medical Research Council …

Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing

M Zecca, K Basler, G Struhl - Development, 1995 - journals.biologists.com
The Drosophila wing is formed by two cell populations, the anterior and posterior
compartments, which are distin-guished by the activity of the selector gene engrailed (en) in …

Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum

W Wurst, AB Auerbach, AL Joyner - Development, 1994 - journals.biologists.com
During mouse development, the homeobox-containing gene En-1 is specifically expressed
across the mid-hindbrain junction, the ventral ectoderm of the limb buds, and in regions of …

Molecular cloning of sequences from wingless, a segment polarity gene in Drosophila: the spatial distribution of a transcript in embryos

NE Baker - The EMBO journal, 1987 - embopress.org
In Drosophila the process of segmentation depends on the function of coordinate, gap, pair‐
rule and segment‐polarity genes. Mutations in segment‐polarity genes cause defects in the …