Antibiotics have transformed modern medicine. They are essential for treating infectious
diseases and enable vital therapies and procedures. However, despite this success, their …

Conventional wet laboratory testing, validations, and synthetic procedures are costly and
time-consuming for drug discovery. Advancements in artificial intelligence (AI) techniques …

Big databases are increasingly widespread and are therefore hard to understand, in
exploratory biomedicine science, big data in health research is highly exciting because data …

Machine learning has emerged with big data technologies and high-performance computing
to create new opportunities for data intensive science in the multi-disciplinary agri …

Antimicrobial resistance threatens a resurgence of life-threatening bacterial infections and
the potential demise of many aspects of modern medicine. Despite intensive drug discovery …

Effective treatments for COVID-19 are urgently needed. However, discovering single-agent
therapies with activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Motivation While drug combination therapies are a well-established concept in cancer
treatment, identifying novel synergistic combinations is challenging due to the size of …

The spread of antimicrobial resistance has become a serious public health concern, making
once-treatable diseases deadly again and undermining the achievements of modern …

Rooted in the mechanism of action of antibiotics and subject to bacterial evolution, antibiotic
resistance is difficult and perhaps impossible to overcome. Nevertheless, strategies can be …

Gene essentiality is a founding concept of genetics with important implications in both
fundamental and applied research. Multiple screens have been performed over the years in …