Structurally dynamic hydrogels for biomedical applications: pursuing a fine balance between macroscopic stability and microscopic dynamics

K Zhang, Q Feng, Z Fang, L Gu, L Bian - Chemical Reviews, 2021 - ACS Publications
Owing to their unique chemical and physical properties, hydrogels are attracting increasing
attention in both basic and translational biomedical studies. Although the classical hydrogels …

Self-assembling peptide EAK16 and RADA16 nanofiber scaffold hydrogel

F Gelain, Z Luo, S Zhang - Chemical reviews, 2020 - ACS Publications
Short peptides are ubiquitous in nature. They are found as hormones, pheromones,
antibacterial and antifungal agents in innate immunity systems, toxins, and pesticides. But …

Cartilage-like protein hydrogels engineered via entanglement

L Fu, L Li, Q Bian, B Xue, J **, J Li, Y Cao, Q Jiang… - Nature, 2023 - nature.com
Load-bearing tissues, such as muscle and cartilage, exhibit high elasticity, high toughness
and fast recovery, but have different stiffness (with cartilage being significantly stiffer than …

Hysteresis‐free nanoparticle‐reinforced hydrogels

X Meng, Y Qiao, C Do, W Bras, C He, Y Ke… - Advanced …, 2022 - Wiley Online Library
The elastic storage and release of mechanical energy has been key to many developments
throughout the history of mankind. Resilience, absent hysteresis, has been an elusive goal …

The extracellular matrix in development

DAC Walma, KM Yamada - Development, 2020 - journals.biologists.com
As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides
both physical support and signaling regulation to cells. Some ECM molecules provide a …

Stretchable hydrogels with low hysteresis and anti-fatigue fracture based on polyprotein cross-linkers

H Lei, L Dong, Y Li, J Zhang, H Chen, J Wu… - Nature …, 2020 - nature.com
Hydrogel-based devices are widely used as flexible electronics, biosensors, soft robots, and
intelligent human-machine interfaces. In these applications, high stretchability, low …

Mechanical Regulation of Polymer Gels

C Xu, Y Chen, S Zhao, D Li, X Tang, H Zhang… - Chemical …, 2024 - ACS Publications
The mechanical properties of polymer gels devote to emerging devices and machines in
fields such as biomedical engineering, flexible bioelectronics, biomimetic actuators, and …

Polymer Adhesion: Seeking New Solutions for an Old Problem#

G Raos, B Zappone - Macromolecules, 2021 - ACS Publications
Polymer adhesion is ubiquitous in both the natural world and human technology. It is also a
complex multiscale phenomenon, such that the solution of adhesion problems requires a …

Low hysteresis hydrogel induced by spatial confinement

J Wang, F Tang, C Yao, L Li - Advanced Functional Materials, 2023 - Wiley Online Library
Stress concentration and hysteresis often occur in polymer hydrogels under large
deformation, affecting their mechanical properties, and durability. Here, a new spatial …

(Macro) molecular self-assembly for hydrogel drug delivery

MJ Webber, ET Pashuck - Advanced drug delivery reviews, 2021 - Elsevier
Hydrogels prepared via self-assembly offer scalable and tunable platforms for drug delivery
applications. Molecular-scale self-assembly leverages an interplay of attractive and …