Nucleotide-derived second messengers are present in all domains of life. In prokaryotes,
most of their functionality is associated with general lifestyle and metabolic adaptations …

The development of resistance to β-lactam antibiotics has made Staphylococcus aureus a
clinical burden on a global scale. MRSA (methicillin-resistant S. aureus) is commonly known …

The opportunistic pathogen Staphylococcus aureus is protected by a cell envelope that is
crucial for viability. In addition to peptidoglycan, lipoteichoic acid (LTA) is an especially …

Bacterial cell division is a complex and highly regulated process requiring the coordination
of many different proteins. Despite substantial work in model organisms, our understanding …

Staphylococcus aureus produces a plethora of virulence factors critical to its ability to
establish an infection and cause disease. We have previously characterized a small …

Background Staphylococcus aureus is the most common bacteria found in skin, soft tissues,
bone, and bone prostheses infections. The aim of this study was to select DNA aptamers for …

Bacterial cell division, with a few exceptions, is driven by FtsZ through a treadmilling
mechanism to remodel and constrict the rigid peptidoglycan (PG) layer. Yet different …

Phages and bacteria have a long history of co-evolution. However, these dynamics of phage-
host interactions are still largely unknown; identification of phage inhibitors that remodel host …