PIEZO channels and newcomers in the mammalian mechanosensitive ion channel family

P Delmas, T Parpaite, B Coste - Neuron, 2022 - cell.com
Many ion channels have been described as mechanosensitive according to various criteria.
Most broadly defined, an ion channel is called mechanosensitive if its activity is controlled by …

[HTML][HTML] Sonogenetics: recent advances and future directions

T Liu, MH Choi, J Zhu, T Zhu, J Yang, N Li, Z Chen… - Brain Stimulation, 2022 - Elsevier
Sonogenetics refers to the use of genetically encoded, ultrasound-responsive mediators for
noninvasive and selective control of neural activity. It is a promising tool for studying neural …

Induction of a torpor-like hypothermic and hypometabolic state in rodents by ultrasound

Y Yang, J Yuan, RL Field, D Ye, Z Hu, K Xu, L Xu… - Nature …, 2023 - nature.com
Torpor is an energy-conserving state in which animals dramatically decrease their metabolic
rate and body temperature to survive harsh environmental conditions. Here, we report the …

Optimized ultrasound neuromodulation for non-invasive control of behavior and physiology

KR Murphy, JS Farrell, J Bendig, A Mitra, C Luff… - Neuron, 2024 - cell.com
Focused ultrasound can non-invasively modulate neural activity, but whether effective
stimulation parameters generalize across brain regions and cell types remains unknown …

PIEZO Ion Channels in Cardiovascular Functions and Diseases

B Coste, P Delmas - Circulation Research, 2024 - Am Heart Assoc
The cardiovascular system provides blood supply throughout the body and as such is
perpetually applying mechanical forces to cells and tissues. Thus, this system is primed with …

Neuromodulation of the peripheral nervous system: Bioelectronic technology and prospective developments

H Song, M Kim, E Kim, J Lee, I Jeong, K Lim, SY Ryu… - …, 2024 - Wiley Online Library
The peripheral nervous system (PNS) is a fascinatingly complex and crucial component of
the human body, responsible for transmitting vital signals throughout the body's intricate …

Noninvasive closed-loop acoustic brain-computer interface for seizure control

J Zou, H Chen, X Chen, Z Lin, Q Yang, C Tie… - …, 2024 - pmc.ncbi.nlm.nih.gov
Rationale: The brain-computer interface (BCI) is core tasks in comprehensively
understanding the brain, and is one of the most significant challenges in neuroscience. The …

A sco** review of current and emerging techniques for evaluation of peripheral nerve health, degeneration, and regeneration: Part 1, neurophysiology

R Mandeville, B Sanchez, B Johnston… - Journal of Neural …, 2023 - iopscience.iop.org
Peripheral neuroregeneration research and therapeutic options are expanding
exponentially. With this expansion comes an increasing need to reliably evaluate and …

Using focused ultrasound to modulate microglial structure and function

S Grewal, E Gonçalves de Andrade… - Frontiers in Cellular …, 2023 - frontiersin.org
Transcranial focused ultrasound (FUS) has the unique ability to target regions of the brain
with high spatial precision, in a minimally invasive manner. Neuromodulation studies have …

Tension activation of mechanosensitive two-pore domain K+ channels TRAAK, TREK-1, and TREK-2

B Sorum, T Docter, V Panico, RA Rietmeijer… - Nature …, 2024 - nature.com
Abstract TRAAK, TREK-1, and TREK-2 are mechanosensitive two-pore domain K+ (K2P)
channels that contribute to action potential propagation, sensory transduction, and muscle …