The etiopathogenesis of endometriosis is a multifactorial process resulting in a
heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still …

Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …

Tea is an important global beverage crop and is largely clonally propagated. Despite
previous studies on the species, its genetic and evolutionary history deserves further …

The African continent is regarded as the cradle of modern humans and African genomes
contain more genetic variation than those from any other continent, yet only a fraction of the …

The domestication of wild emmer wheat led to the selection of modern durum wheat, grown
mainly for pasta production. We describe the 10.45 gigabase (Gb) assembly of the genome …

Systemic lupus erythematosus (SLE), a worldwide autoimmune disease with high
heritability, shows differences in prevalence, severity and age of onset among different …

Since its introduction in 2011 the variant call format (VCF) has been widely adopted for
processing DNA and RNA variants in practically all population studies—as well as in …

Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …

Hypoxia occurs naturally at high-altitudes and pathologically in hypoxic solid tumors. Here,
we report that genes involved in various human cancers evolved rapidly in Tibetans and six …

Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk
globally. Large-scale schizophrenia genetic studies have reported primarily on European …