Multienzyme‐like nanozymes: regulation, rational design, and application

J Sheng, Y Wu, H Ding, K Feng, Y Shen… - Advanced …, 2024 - Wiley Online Library
Nanomaterials with more than one enzyme‐like activity are termed multienzymic
nanozymes, and they have received increasing attention in recent years and hold huge …

Catalase‐like nanozymes: Classification, catalytic mechanisms, and their applications

D Xu, L Wu, H Yao, L Zhao - Small, 2022 - Wiley Online Library
The field of nanozymes has developed rapidly over the past decade. Among various
oxidoreductases mimics, catalase (CAT)‐like nanozyme, acting as an essential part of the …

Designing nanozymes for in vivo applications

R Zhang, B Jiang, K Fan, L Gao, X Yan - Nature Reviews …, 2024 - nature.com
Biocatalytic drugs, including natural and artificial enzymes that can accelerate biochemical
reactions, are promising tools to address redox imbalances, metabolic disorders and …

Guiding transition metal‐doped hollow cerium tandem nanozymes with elaborately regulated multi‐enzymatic activities for intensive chemodynamic therapy

S Dong, Y Dong, B Liu, J Liu, S Liu, Z Zhao… - Advanced …, 2022 - Wiley Online Library
Clinical applications of nanozyme‐initiated chemodynamic therapy (NCDT) have been
severely limited by the poor catalytic efficiency of nanozymes, insufficient endogenous …

Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

Structure and activity of nanozymes: Inspirations for de novo design of nanozymes

Z Wang, R Zhang, X Yan, K Fan - Materials Today, 2020 - Elsevier
Nanozymes, nanomaterials with enzyme-like activities, are becoming powerful competitors
and potential substitutes for natural enzymes because of their excellent performance …

A review on metal-and metal oxide-based nanozymes: properties, mechanisms, and applications

Q Liu, A Zhang, R Wang, Q Zhang, D Cui - Nano-micro letters, 2021 - Springer
Since the ferromagnetic (Fe 3 O 4) nanoparticles were firstly reported to exert enzyme-like
activity in 2007, extensive research progress in nanozymes has been made with deep …

Superoxide dismutase nanozymes: an emerging star for anti-oxidation

H Zhao, R Zhang, X Yan, K Fan - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Superoxide dismutases (SODs) are a group of metalloenzymes that catalyze the dismutation
of superoxide radicals (O2˙−) into hydrogen peroxide (H2O2) and oxygen (O2). As the first …

Nanozymes: activity origin, catalytic mechanism, and biological application

W Yang, X Yang, L Zhu, H Chu, X Li, W Xu - Coordination Chemistry …, 2021 - Elsevier
Nanozymes are nanomaterials with excellent enzyme-like characteristics. Compared with
natural enzymes, nanozymes possess significant advantages, such as low cost, high …

[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

T Zhao, W Wu, L Sui, Q Huang, Y Nan, J Liu, K Ai - Bioactive Materials, 2022 - Elsevier
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …