Alcohol is one of the most widely consumed psychoactive drugs globally. Hazardous
drinking, defined by quantity and frequency of consumption, is associated with acute and …

Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use
and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent …

Drug addiction may be a goal-directed choice driven by excessive drug value in negative
affective states, a habit driven by strong stimulus− response associations, or a compulsion …

Neuroadaptations that occur in response to repeated substance use diminish the euphoria
that is produced by the acute use of a drug and increase levels of physical and emotional …

Recognition and Management of Withdrawal Delirium (Delirium Tremens) | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

In this review, we detail the clinical evidence supporting the role of psychological and
physiological stress in instrumental motivation for alcohol consumption during the …

Sleep‐related complaints are widely prevalent in those with alcohol dependence (AD). AD is
associated not only with insomnia, but also with multiple sleep‐related disorders as a …

Stress is commonly regarded as an important trigger for relapse and a significant factor that
promotes increased motivation to drink in some individuals. However, the relationship …

Dysregulation of pain neurocircuitry and neurochemistry has been increasingly recognized
as playing a critical role in a diverse spectrum of diseases including migraine, fibromyalgia …

Background: Epidemiological studies reveal that individuals who report risky substance use
are generally less likely to meet physical activity guidelines (with the exception of certain …