Flavonoids are a category of plant-derived compounds which exhibit a large number of
health-related effects. One of the most well-known and studied flavonoids is kaempferol …

Genome-scale metabolic models (GEMs) computationally describe gene-protein-reaction
associations for entire metabolic genes in an organism, and can be simulated to predict …

Malaria is one of the most devastating infectious diseases of humans. It is problematic
clinically and economically as it prevails in poorer countries and regions, strongly hindering …

Malaria is a severe disease caused by parasites of the genus Plasmodium, which is
transmitted to humans by a bite of an infected female mosquito of the species Anopheles …

Plasmodium spp. parasites are the causative agents of malaria in humans and animals, and
they are exceptionally diverse in their morphology and life cycles. They grow and develop in …

In the mosquito–human life cycle, the six species of malaria parasites infecting humans
(Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale wallickeri, Plasmodium …

In the malaria parasite Plasmodium falciparum, the switch from asexual multiplication to
sexual differentiation into gametocytes is essential for transmission to mosquitos. The …

The apicomplexan parasite Cryptosporidium is a leading global cause of severe diarrhoeal
disease and an important contributor to early childhood mortality. Currently, there are no …

Human to vector transmission of malaria requires that some blood-stage parasites abandon
asexual growth and convert into non-replicating sexual forms called gametocytes. The initial …

Sexual differentiation of malaria parasites from the asexual blood stage into gametocytes is
an essential part of the life cycle, as gametocytes are the form that is taken up by the …