Sensitive optical biosensors for unlabeled targets: A review

X Fan, IM White, SI Shopova, H Zhu, JD Suter… - analytica chimica acta, 2008 - Elsevier
This article reviews the recent progress in optical biosensors that use the label-free
detection protocol, in which biomolecules are unlabeled or unmodified, and are detected in …

Biomarker detection technologies and future directions

SB Nimse, MD Sonawane, KS Song, T Kim - Analyst, 2016 - pubs.rsc.org
Biomarkers play a vital role in disease detection and treatment follow-up. It is important to
note that diseases in the early stage are typically treated with the greatest probability of …

Progress of new label-free techniques for biosensors: A review

S Sang, Y Wang, Q Feng, Y Wei, J Ji… - Critical reviews in …, 2016 - Taylor & Francis
The detection techniques used in biosensors can be broadly classified into label-based and
label-free. Label-based detection relies on the specific properties of labels for detecting a …

Antibody-based protein multiplex platforms: technical and operational challenges

AA Ellington, IJ Kullo, KR Bailey, GG Klee - Clinical chemistry, 2010 - academic.oup.com
Background: The measurement of multiple protein biomarkers may refine risk stratification in
clinical settings. This concept has stimulated development of multiplexed immunoassay …

Point-of-care biosensor systems for cancer diagnostics/prognostics

SA Soper, K Brown, A Ellington, B Frazier… - Biosensors and …, 2006 - Elsevier
With the growing number of fatalities resulting from the 100 or so cancer-related diseases,
new enabling tools are required to provide extensive molecular profiles of patients to guide …

Label-free optical resonant sensors for biochemical applications

C Ciminelli, CM Campanella, F Dell'Olio… - Progress in Quantum …, 2013 - Elsevier
For a number of years, the scientific community has been paying growing attention to the
monitoring and enhancement of public health and the quality of life through the detection of …

Bacterial detection: From microscope to smartphone

SCB Gopinath, TH Tang, Y Chen, M Citartan… - Biosensors and …, 2014 - Elsevier
The ubiquitous nature of bacteria enables them to survive in a wide variety of environments.
Hence, the rise of various pathogenic species that are harmful to human health raises the …

Critical assessment of relevant methods in the field of biosensors with direct optical detection based on fibers and waveguides using plasmonic, resonance, and …

G Gauglitz - Analytical and Bioanalytical Chemistry, 2020 - Springer
Direct optical detection has proven to be a highly interesting tool in biomolecular interaction
analysis to be used in drug discovery, ligand/receptor interactions, environmental analysis …

Aptamer-based 'point-of-care testing'

SCB Gopinath, T Lakshmipriya, Y Chen… - Biotechnology …, 2016 - Elsevier
Aptamers are single-stranded oligonucleotides that can be artificially generated by a method
called Systematic evolution of ligands by exponential enrichment (SELEX). The generated …

Emerging tools for real‐time label‐free detection of interactions on functional protein microarrays

N Ramachandran, DN Larson, PRH Stark… - The FEBS …, 2005 - Wiley Online Library
The availability of extensive genomic information and content has spawned an era of high‐
throughput screening that is generating large sets of functional genomic data. In particular …