Poly (ethylene glycol) alternatives in biomedical applications

X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …

Enhanced antitumor efficacy by a cascade of reactive oxygen species generation and drug release

S Wang, G Yu, Z Wang, O Jacobson, LS Lin… - Angewandte …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) can be used not only as a therapeutic agent for
chemodynamic therapy (CDT), but also as a stimulus to activate release of antitumor drugs …

[HTML][HTML] Recent advances in degradable synthetic polymers for biomedical applications‐Beyond polyesters

M Dirauf, I Muljajew, C Weber, US Schubert - Progress in Polymer Science, 2022 - Elsevier
Polyesters have been studied intensely over the last few decades and proved to be suitable
for a wide range of applications. Despite all benefits, drawbacks such as eg the acidification …

Hierarchical tumor microenvironment‐responsive nanomedicine for programmed delivery of chemotherapeutics

S Wang, G Yu, Z Wang, O Jacobson, R Tian… - Advanced …, 2018 - Wiley Online Library
Nanomedicines have been demonstrated to have passive or active tumor targeting
behaviors, which are promising for cancer chemotherapy. However, most nanomedicines …

ROS-responsive nanoparticles based on amphiphilic hyperbranched polyphosphoester for drug delivery: light-triggered size-reducing and enhanced tumor …

H **, T Zhu, X Huang, M Sun, H Li, X Zhu, M Liu, Y **e… - Biomaterials, 2019 - Elsevier
Up to now, limited tumor penetration and poor therapeutic efficiency of drug-loaded
nanoparticles are still the major challenges in nanomedicines for cancer chemotherapy. In …

Stimulus‐Responsive Nano‐Prodrug Strategies for Cancer Therapy: A Focus on Camptothecin Delivery

B Chu, H Deng, T Niu, Y Qu, Z Qian - Small methods, 2024 - Wiley Online Library
Camptothecin (CPT) is a highly cytotoxic molecule with excellent antitumor activity against
various cancers. However, its clinical application is severely limited by poor water solubility …

Advanced biomaterials derived from functional polyphosphoesters: synthesis, properties, and biomedical applications

J Li, Y Hao, H Wang, M Zhang, J He… - ACS Applied Materials & …, 2024 - ACS Publications
Polyphosphoesters (PPEs) represent an innovative class of biodegradable polymers, with
the phosphate ester serving as the core repeating unit of their polymeric backbone …

Phosphate ester functionalized fluorene-benzothiadiazole alternating copolymer/hydroxylated g-C3N4 heterojunctions for efficient hydrogen evolution under visible …

X Pang, Y Li, X Wu, B Zhang, M Hao, Y Zhu… - Journal of Colloid and …, 2023 - Elsevier
It is highly desirable to explore functionalized polymer semiconductor/gC 3 N 4
heterojunction photocatalysts with the tight interfacial connection for promoting the …

[HTML][HTML] Zwitterionic-to-cationic charge conversion polyprodrug nanomedicine for enhanced drug delivery

S Wang, F Zhang, G Yu, Z Wang, O Jacobson, Y Ma… - Theranostics, 2020 - ncbi.nlm.nih.gov
Zwitterionic surface modification is a promising strategy for nanomedicines to achieve
prolonged circulation time and thus effective tumor accumulation. However, zwitterion …

Strategies To Design and Synthesize Polymer‐Based Stimuli‐Responsive Drug‐Delivery Nanosystems

X Qin, Y Li - ChemBioChem, 2020 - Wiley Online Library
The emergence and development of nanomedicine have alleviated problems existing in
traditional chemotherapy drugs, such as short lifetime, concomitant side effects, and weak …