Tumor immune microenvironment and genetic alterations in mesothelioma
S Hiltbrunner, L Mannarino, MB Kirschner… - Frontiers in …, 2021 - frontiersin.org
Malignant pleural mesothelioma (MPM) is a rare and fatal disease of the pleural lining. Up to
80% of the MPM cases are linked to asbestos exposure. Even though its use has been …
80% of the MPM cases are linked to asbestos exposure. Even though its use has been …
Emerging avenues in immunotherapy for the management of malignant pleural mesothelioma
SG Gray - BMC Pulmonary Medicine, 2021 - Springer
Background The role of immunotherapy in cancer is now well-established, and therapeutic
options such as checkpoint inhibitors are increasingly being approved in many cancers such …
options such as checkpoint inhibitors are increasingly being approved in many cancers such …
Immune-related pan-cancer gene expression signatures of patient survival revealed by NanoString-based analyses
The immune system plays a central role in the onset and progression of cancer. A better
understanding of transcriptional changes in immune cell-related genes associated with …
understanding of transcriptional changes in immune cell-related genes associated with …
Results of the Meso-ORIGINS feasibility study regarding collection of matched benign-mesothelioma tissue pairs by longitudinal surveillance
K Ferguson, M Neilson, R Mercer, J King, K Marshall… - BMJ open, 2023 - bmjopen.bmj.com
Objectives To assess key elements of the design for Meso-ORIGINS (Mesothelioma
Observational study of RIsk prediction and Generation of paired benign-meso tissue …
Observational study of RIsk prediction and Generation of paired benign-meso tissue …
In vitro cell culture of patient derived malignant pleural and peritoneal effusions for personalised drug screening
CG Wu, F Chiovaro, A Curioni-Fontecedro… - Journal of translational …, 2020 - Springer
Background Malignant serous effusion (MSE) denotes a manifestation of metastatic disease
with typical high concentrations of both cancer and immune cells, making them an ideal …
with typical high concentrations of both cancer and immune cells, making them an ideal …
Hormonal receptor status determines prognostic significance of FGFR2 in invasive breast carcinoma
Simple Summary FGFR2-ER-PR crosstalk leads to hormone-independent progression of
breast cancer. In vitro, FGFR2 stimulates PR transcriptional activity and mediates resistance …
breast cancer. In vitro, FGFR2 stimulates PR transcriptional activity and mediates resistance …
Lung adenocarcinoma patients with malignant pleural effusions in hot adaptive immunity status have a longer overall survival
CG Wu, R Casanova, F Mairinger… - Frontiers in …, 2022 - frontiersin.org
Malignant pleural effusion (MPE) is a common complication of lung adenocarcinoma
(LADC) which is associated with a dismal prognosis. We investigated the prognostic role of …
(LADC) which is associated with a dismal prognosis. We investigated the prognostic role of …
Ancillary studies for serous fluids
Spread of malignancies to serous cavities represents advanced stage disease that
necessitates systemic treatment. Immunochemistry (IC) is an indispensable tool to ascertain …
necessitates systemic treatment. Immunochemistry (IC) is an indispensable tool to ascertain …
Evolution of mesothelioma from benign asbestos pleural inflammation
K Ferguson - 2025 - theses.gla.ac.uk
Pleural Mesothelioma (PM) is an incurable disease with a poor life expectancy. It is most
commonly associated with asbestos exposure and the latency period from exposure to PM …
commonly associated with asbestos exposure and the latency period from exposure to PM …
Malignant Pleural Effusion: Finding Our Way Through Highly Dynamic Times
AT Woods - 2024 - search.proquest.com
Malignant pleural effusion (MPE) is a serious complication occurring when cancer cells are
found in the pleural cavity surrounding the lung. MPE is typically associated with highly …
found in the pleural cavity surrounding the lung. MPE is typically associated with highly …