Recent trends in targeting miRNAs for cancer therapy

V Shah, J Shah - Journal of Pharmacy and Pharmacology, 2020 - academic.oup.com
Objectives MicroRNAs (miRNAs) are a type of small noncoding RNA employed by the cells
for gene regulation. A single miRNA, typically 22 nucleotides in length, can regulate the …

[HTML][HTML] MicroRNAs as novel biomarkers for colorectal cancer: New outlooks

N Shirafkan, B Mansoori, A Mohammadi… - Biomedicine & …, 2018 - Elsevier
Colorectal cancer is one of the most prevalent cancers with high mortality in the world.
MicroRNAs are a class of small non-coding RNAs that regulate gene expression through …

Hsa_circ_0003998 promotes epithelial to mesenchymal transition of hepatocellular carcinoma by sponging miR-143-3p and PCBP1

L Song, G Qiao, J Yu, C Yang, Y Chen, Z Deng… - Journal of Experimental …, 2020 - Springer
Abstract Background Circular RNAs (circRNAs) play a critical regulatory role in cancer
progression. However, the underlying mechanisms of circRNAs in hepatocellular carcinoma …

[HTML][HTML] Regulatory mechanisms of miR-145 expression and the importance of its function in cancer metastasis

T Zeinali, B Mansoori, A Mohammadi… - Biomedicine & …, 2019 - Elsevier
MicroRNAs are post-transcriptional mediators of gene expression and regulation, which play
influential roles in tumorigenesis and cancer metastasis. The expression of tumor …

miR‐330 suppresses EMT and induces apoptosis by downregulating HMGA2 in human colorectal cancer

B Mansoori, A Mohammadi… - Journal of cellular …, 2020 - Wiley Online Library
MicroRNAs (miRNAs) are important molecular regulatorsof cellular signaling and behavior.
They alter gene expression by targeting messenger RNAs, including those encoding …

Recent advances in novel miRNA mediated approaches for targeting breast cancer

SM Ahmadi, S Amirkhanloo… - Journal of Drug …, 2023 - Taylor & Francis
Breast cancer (BC) is considered one of the most frequent cancers among woman
worldwide. While conventional therapy has been successful in treating many cases of breast …

Targeting Wnt/β-catenin signaling by microRNAs as a therapeutic approach in chemoresistant osteosarcoma

F Hosseini, F Alemi, F Malakoti, A Mahmoodpoor… - Biochemical …, 2021 - Elsevier
Osteosarcoma (OS) is an adolescent and young adult malignancy that mostly occurs in long
bones. The treatment of OS is still a big challenge for clinicians due to increasing …

CD133: An emerging prognostic factor and therapeutic target in colorectal cancer

M Akbari, N Shomali, A Faraji… - Cell biology …, 2020 - Wiley Online Library
Colorectal cancer (CRC) is one of the leading causes of death worldwide. Recently, the role
of cancer stem cells (CSCs) has been highlighted as a crucial emerging factor in …

The roles of microRNA in human cervical cancer

J Miao, JM Regenstein, D Xu, D Zhou, H Li… - Archives of biochemistry …, 2020 - Elsevier
Although a potentially preventable disease, cervical cancer (CC) is the second most
commonly diagnosed gynaecological cancer with at least 530,000 new cases annually, and …

miRNAs that regulate apoptosis in breast cancer and cervical cancer

EAV Beilankouhi, MS Maghsoodi, MZ Sani… - Cell Biochemistry and …, 2024 - Springer
In today's world, one of the main problems is cancer, which still has a long way to go to cure
it, and it brings a lot of financial and emotional costs to the people of society and …