Abstract Magnesium (Mg 2+) is an essential ion to the human body, playing an instrumental
role in supporting and sustaining health and life. As the second most abundant intracellular …

Magnesium, the second most abundant cellular cation after potassium, is essential to
regulate numerous cellular functions and enzymes, including ion channels, metabolic …

Over the past decades, hypomagnesemia (serum Mg2+< 0.7 mmol/L) has been strongly
associated with type 2 diabetes mellitus (T2DM). Patients with hypomagnesemia show a …

The epidermal growth factor receptor (EGFR) is the prototypical member of a family of
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …

Arterial hypertension is a disease with a complex pathogenesis. Despite considerable
knowledge about this socially significant disease, the role of magnesium deficiency (MgD) …

Answer questions and earn CME/CNE Advances in genomics and molecular biology have
identified aberrant proteins in cancer cells that are attractive targets for cancer therapy …

The distal convoluted tubule is the nephron segment that lies immediately downstream of
the macula densa. Although short in length, the distal convoluted tubule plays a critical role …

The transient receptor potential melastatin-subfamily member 7 (TRPM7) is a ubiquitously
expressed chanzyme that possesses an ion channel permeable to the divalent cations …

Hypomagnesemia is 10-fold more common in individuals with type 2 diabetes (T2D) than in
the healthy population. Factors that are involved in this high prevalence are low Mg2+ …

In 1962, epidermal growth factor (EGF) was discovered by Dr. Stanley Cohen while studying
nerve growth factor (NGF). It was soon recognized that EGF is the prototypical member of a …