Organic solvent nanofiltration in pharmaceutical applications

H **ao, Y Feng, WRF Goundry… - … Process Research & …, 2024 - ACS Publications
Separation and purification in organic solvents are indispensable procedures in
pharmaceutical manufacturing. However, they still heavily rely on the conventional …

Continuous microfluidic antisolvent crystallization as a bottom-up solution for the development of long-acting injectable formulations

S Nandi, L Verstrepen, M Hugo Silva, L Padrela… - Pharmaceutics, 2024 - mdpi.com
A bottom-up approach was investigated to produce long-acting injectable (LAI) suspension-
based formulations to overcome specific limitations of top-down manufacturing methods by …

[HTML][HTML] Bottom-up production of injectable itraconazole suspensions using membrane technology

F Anjum, T Viville, S Nandi, M Wessner… - International Journal of …, 2024 - Elsevier
Bottom-up production of active pharmaceutical ingredient (API) crystal suspensions offers
advantages in surface property control and operational ease over top-down methods …

[HTML][HTML] Tailoring the use of excipients in bottom-up production of naproxen crystal suspensions via membrane technology

F Anjum, M Wessner, B De Witte, N Al-Rifai… - International Journal of …, 2024 - Elsevier
Long-acting crystal suspensions of active pharmaceutical ingredients (API) mostly
comprised of an API, a suspension media (water) and excipients and provide sustained API …